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enastron

a kinesin Eg5 inhibitor and antiproliferative agent; structure in first source

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinazolines: 402
      - enastron: 3
Inorganic Chemicals: 9
- Thiones: 70
  - enastron: 3
Organic Chemicals: 133
- Sulfur Compounds: 278
  - Thiones: 70
    - enastron: 3

Experts

1.	Sun, Linlin: 1 article (05/2014)
2.	Sun, Xiaodong: 1 article (05/2014)
3.	Xie, Songbo: 1 article (05/2014)
4.	Yu, Haiyang: 1 article (05/2014)
5.	Zhong, Diansheng: 1 article (05/2014)
6.	Bernhardt, Günther: 1 article (02/2007)
7.	Buschauer, Armin: 1 article (02/2007)
8.	Gartner, Michael: 1 article (02/2007)
9.	Giannis, Athanassios: 1 article (02/2007)
10.	Gross, Dietmar: 1 article (02/2007)

Related Diseases

1.	B-Cell Lymphoma (Lymphoma, B Cell) 06/22/2023 - "In this context, we investigated the cytotoxic activity of enastron analogues on three human cell lines PRI (lymphoblastic cell line) derived from B-cell lymphoma. "
2.	Lung Neoplasms (Lung Cancer) 05/09/2014 - "By comparing with enastron, here we report that dimethylenastron prevents the growth of pancreatic and lung cancer cells more effectively, by halting mitotic progression and triggering apoptosis. "
3.	Glioblastoma (Glioblastoma Multiforme) 02/01/2007 - "Therefore, we studied the effects of the new monastrol analogues enastron, dimethylenastron and vasastrol VS-83 on the proliferation of human glioblastoma cells in the kinetic crystal violet assay. "

Related Drugs and Biologics

1.	dimethylenastron
2.	Gentian Violet (Violet, Crystal)
3.	vasastrol VS-83
4.	monastrol