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MLN8054

antineoplastic; an orally active small-molecule inhibitor of Aurora A kinase; structure in first source
Also Known As:
4-((9-chloro-7-(2,6-difluorophenyl)-5H-pyrimidol(5,4-d)(2)benzazepin-2-yl)amino)benzoic acid
Networked: 18 relevant articles (0 outcomes, 6 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Stringer, Bradley: 4 articles (04/2011 - 03/2007)
2. Bowman, Douglas: 4 articles (02/2011 - 06/2007)
3. Ecsedy, Jeffrey A: 4 articles (02/2011 - 03/2007)
4. Danaee, Hadi: 3 articles (04/2011 - 10/2010)
5. Liu, Hua: 3 articles (04/2011 - 10/2010)
6. Ecsedy, Jeffrey: 3 articles (04/2011 - 11/2008)
7. Galvin, Katherine: 3 articles (04/2011 - 06/2007)
8. Shinde, Vaishali: 3 articles (02/2011 - 06/2007)
9. Chakravarty, Arijit: 3 articles (02/2011 - 06/2007)
10. Zhang, Mengkun: 3 articles (02/2011 - 03/2007)

Related Diseases

1. Neoplasms (Cancer)
2. Prostatic Neoplasms (Prostate Cancer)
3. Aneuploidy (Aneuploid)
4. Melanoma (Melanoma, Malignant)
5. Thyroid Neoplasms (Thyroid Cancer)

Related Drugs and Biologics

1. aurora kinase (aurora A kinase)
2. Nocodazole
3. Biological Markers (Surrogate Marker)
4. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
5. Vascular Endothelial Growth Factor Receptors (VEGF Receptors)
6. Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)
7. von Willebrand Factor
8. Epidermal Growth Factor (EGF)
9. MLN 8237
10. 2- ((3- ((4- ((5- (2- ((3- fluorophenyl)amino)- 2- oxoethyl)- 1H- pyrazol- 3- yl)amino)quinazolin- 7- yl)oxy)propyl)(ethyl)amino)ethyl dihydrogen phosphate

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Oral Administration