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CHIR-124

a potent inhibitor of Chk1 that potentiates the cytotoxicity of topoisomerase I poisons in vitro and in vivo; structure in first source
Also Known As:
((S)-3-(1H-benzo(d)imidazol-2-yl)-6-chloro-4-quinuclidin-3-ylamino)quinolin-2(1H)-one
Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Leteur, Céline: 1 article (04/2009)
2. Zhang, Ping: 1 article (04/2009)
3. Bourhis, Jean: 1 article (04/2009)
4. Castedo, Maria: 1 article (04/2009)
5. Tao, Yungan: 1 article (04/2009)
6. Golsteyn, Roy M: 1 article (04/2009)
7. Pierré, Alain: 1 article (04/2009)
8. Kroemer, Guido: 1 article (04/2009)
9. Deutsch, Eric: 1 article (04/2009)
10. Yang, Ceyao: 1 article (04/2009)

Related Diseases

1. Tetraploidy
2. Polyploidy
3. Neoplasms (Cancer)
4. Breast Neoplasms (Breast Cancer)

Related Drugs and Biologics

1. DNA (Deoxyribonucleic Acid)
2. irinotecan (Camptosar)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)