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SRM 1597

extracted from coal tar

Also Known As:

SRM-1597; SRM1597

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        SRM 1597: 2
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - SRM 1597: 2

Experts

1.	Baird, William M: 2 articles (03/2007 - 02/2005)
2.	Dashwood, Wan-Mohaiza: 2 articles (03/2007 - 02/2005)
3.	Mahadevan, Brinda: 2 articles (03/2007 - 02/2005)
4.	Marston, Charis P: 2 articles (03/2007 - 02/2005)
5.	Brooks, Eric: 1 article (03/2007)
6.	Doehmer, Johannes: 1 article (03/2007)
7.	Luch, Andreas: 1 article (03/2007)
8.	Pereira, Cliff: 1 article (03/2007)
9.	Li, Yonghai: 1 article (02/2005)
10.	Pereira, Clifford: 1 article (02/2005)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 02/01/2005 - "To determine the effects of SRM 1597 on PAH activation in human cells, we investigated the PAH-DNA adduct formation in the human mammary carcinoma-derived cell line MCF-7. " 03/15/2007 - "A complex mixture of polycyclic aromatic hydrocarbons (PAH) extracted from coal tar, the Standard Reference Material (SRM) 1597, was recently shown to decrease the levels of DNA binding of the 2 strong carcinogens benzo[a]pyrene (BP) and dibenzo[a,l]pyrene (DBP) in the human mammary carcinoma-derived cell line MCF-7 (Mahadevan et al., Chem Res Toxicol 2005;18:224-231). "
2.	Carcinogenesis 02/01/2005 - "A complex mixture of polycyclic aromatic hydrocarbons (PAH) extracted from coal tar, standard reference material (SRM) 1597, has been shown to initiate tumor formation in mouse initiation-promotion assays in our laboratory [(2001) Carcinogenesis 22 (7), 1077-1086]. "
3.	Neoplasms (Cancer) 02/01/2005 - "A complex mixture of polycyclic aromatic hydrocarbons (PAH) extracted from coal tar, standard reference material (SRM) 1597, has been shown to initiate tumor formation in mouse initiation-promotion assays in our laboratory [(2001) Carcinogenesis 22 (7), 1077-1086]. "

Related Drugs and Biologics

1.	Complex Mixtures
2.	Polycyclic Aromatic Hydrocarbons (Polynuclear Aromatic Hydrocarbons)
3.	Coal Tar (Estar)
4.	DNA (Deoxyribonucleic Acid)
5.	Carcinogens
6.	Benzo(a)pyrene
7.	polycyclic aromatic hydrocarbons-DNA adduct
8.	dibenzo(a,l)pyrene