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2- (4- methylphenyll)- 2,3- dihydro- N- (2- hydroxy- 3- (4- (2- (1- methylethoxy)phenyl)- 1- piperazinyl)propyl)- 1,3- dioxo- 1H- isoindole- 5- carboxamide

an alpha-1A adrenergic receptor antagonist; structure in first source

Also Known As:

RWJ 69471; RWJ-69471; RWJ69471

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Phthalic Acids: 1
      - Phthalimides: 12
        2-(4-methylphenyll)-2,3-dihydro-N-(2-hydroxy-3-(4-(2-(1-methylethoxy)phenyl)-1-piperazinyl)propyl)-1,3-dioxo-1H-isoindole-5-carboxamide: 1
- Imides: 79
  - Phthalimides: 12
    - 2-(4-methylphenyll)-2,3-dihydro-N-(2-hydroxy-3-(4-(2-(1-methylethoxy)phenyl)-1-piperazinyl)propyl)-1,3-dioxo-1H-isoindole-5-carboxamide: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperazines: 26
    - 2-(4-methylphenyll)-2,3-dihydro-N-(2-hydroxy-3-(4-(2-(1-methylethoxy)phenyl)-1-piperazinyl)propyl)-1,3-dioxo-1H-isoindole-5-carboxamide: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Isoindoles: 18
      - Phthalimides: 12
        2-(4-methylphenyll)-2,3-dihydro-N-(2-hydroxy-3-(4-(2-(1-methylethoxy)phenyl)-1-piperazinyl)propyl)-1,3-dioxo-1H-isoindole-5-carboxamide: 1

Experts

1.	Kuo, G H: 1 article (10/2006)
2.	McKown, L A: 1 article (10/2006)
3.	Wu, W N: 1 article (10/2006)

Related Diseases

1.	Dehydration (Water Stress) 10/01/2006 - "The formation of RWJ-69205 and RWJ-69471 metabolites are via the following five metabolic pathways: 1. phenylhydroxylation, 2. O-dealkylation, 3. oxidative N-dealkylation, 4. N-dephenylation, and 5. dehydration. "

Related Drugs and Biologics

1.	2- (3- fluorophenyl)- 2,3- dihydro- N- (2- hydroxy- 3- (4- (2- (1- methylethoxy)phenyl)- 1- piperazinyl)propyl)- 1,3- dioxo- 1H- isoindole- 5- carboxamide