|1.||Thurston, D E: 1 article (02/2007)|
|2.||Loadman, P M: 1 article (02/2007)|
|3.||Bibby, M C: 1 article (02/2007)|
|4.||Schultz, R: 1 article (02/2007)|
|5.||Burger, A M: 1 article (02/2007)|
|6.||Fiebig, H H: 1 article (02/2007)|
02/01/2007 - "DRH-417 emerged from the EORTC-Drug Discovery Committee and NCI 60 cell line in vitro screening programs as a potent antiproliferative agent with differential sensitivity towards certain cancer types such as melanoma, breast and renal cell carcinoma (mean IC(50) = 3 nM). "
02/01/2007 - "The pyrrolobenzodiazepine monomer DRH-417 is a member of the anthramycin group of anti-tumor antibiotics that bind covalently to the N2 of guanine within the minor groove of DNA. "
|2.||Melanoma (Melanoma, Malignant)
|3.||Renal Cell Carcinoma (Grawitz Tumor)
|2.||DNA (Deoxyribonucleic Acid)
|3.||Anti-Bacterial Agents (Antibiotics)