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digeranyl bisphosphonate

structure in first source

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - digeranyl bisphosphonate: 3
- Organophosphorus Compounds: 300
  - Organophosphonates: 424
    - Diphosphonates: 11565
      - digeranyl bisphosphonate: 3

Experts

1.	Agabiti, Sherry S: 1 article (01/2017)
2.	Li, Jin: 1 article (01/2017)
3.	Wiemer, Andrew J: 1 article (01/2017)
4.	Carter, A Brent: 1 article (09/2015)
5.	Glogauer, Michael: 1 article (09/2015)
6.	Gu, Linlin: 1 article (09/2015)
7.	Hohl, Raymond: 1 article (09/2015)
8.	Larson-Casey, Jennifer L: 1 article (09/2015)
9.	Murthy, Shubha: 1 article (09/2015)
10.	Neighbors, Jeffrey D: 1 article (09/2015)

Related Diseases

1.	Lung Injury 09/01/2015 - "By targeting the isoprenoid pathway with a novel agent, digeranyl bisphosphonate (DGBP), which impairs geranylgeranylation, we demonstrate that Rac1 mitochondrial import, mitochondrial oxidative stress, and progression of the fibrotic response to lung injury are significantly attenuated. "
2.	Prostatic Neoplasms (Prostate Cancer) 05/01/2011 - "Herein, we show that an inhibitor of FDPS (zoledronate) and an inhibitor of GGDPS (digeranyl bisphosphonate, DGBP) induce autophagy in PC3 prostate cancer and MDA-MB-231 breast cancer cells as measured by accumulation of the autophagic marker LC3-II. "
3.	Lymphoid Leukemia 01/01/2017 - "Here, we compared the effects of a farnesyl diphosphate synthase inhibitor, zoledronate, and a geranylgeranyl diphosphate synthase (GGDPS) inhibitor, digeranyl bisphosphonate (DGBP), on lymphocytic leukemia cell proliferation and apoptosis. "
4.	Breast Neoplasms (Breast Cancer) 05/01/2011 - "Herein, we show that an inhibitor of FDPS (zoledronate) and an inhibitor of GGDPS (digeranyl bisphosphonate, DGBP) induce autophagy in PC3 prostate cancer and MDA-MB-231 breast cancer cells as measured by accumulation of the autophagic marker LC3-II. "

Related Drugs and Biologics

1.	Zoledronic Acid (Zometa)
2.	Farnesyltranstransferase (Farnesyltransferase)
3.	Geranyltranstransferase
4.	Terpenes (Terpenoids)