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6- (2- (5- chloro- 2- (((2,4- difluorophenyl)methyl)oxy)phenyl)- 1- cyclopenten- 1- yl)- 2- pyridinecarboxylic acid

structure in first source

Also Known As:

GW848687X

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Alicyclic Hydrocarbons: 1
      - Cycloparaffins: 6
        Cyclopentanes: 58
        6-(2-(5-chloro-2-(((2,4-difluorophenyl)methyl)oxy)phenyl)-1-cyclopenten-1-yl)-2-pyridinecarboxylic acid: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - 6-(2-(5-chloro-2-(((2,4-difluorophenyl)methyl)oxy)phenyl)-1-cyclopenten-1-yl)-2-pyridinecarboxylic acid: 2

Experts

1.	Brown, Susan H: 2 articles (05/2009 - 01/2007)
2.	Chowdhury, Anita: 2 articles (05/2009 - 01/2007)
3.	Clayton, Nicholas M: 2 articles (05/2009 - 01/2007)
4.	Giblin, Gerard M P: 2 articles (05/2009 - 01/2007)
5.	Hall, Adrian: 2 articles (05/2009 - 01/2007)
6.	Hurst, David N: 2 articles (05/2009 - 01/2007)
7.	Naylor, Alan: 2 articles (05/2009 - 01/2007)
8.	Scoccitti, Tiziana: 2 articles (05/2009 - 01/2007)
9.	Billinton, Andy: 1 article (05/2009)
10.	Gibson, Mairi: 1 article (05/2009)

Related Diseases

1.

01/15/2007 - "From this series, GW848687X was shown to have an excellent profile in models of inflammatory pain and was selected as a development candidate."
05/01/2009 - "GSK269984A was designed to overcome development issues encountered with previous EP(1) antagonists such as GW848687X and was found to display excellent activity in preclinical models of inflammatory pain. "
01/15/2007 - "The discovery of 6-[2-(5-chloro-2-{[(2,4-difluorophenyl)methyl]oxy}phenyl)-1-cyclopenten-1-yl]-2-pyridinecarboxylic acid, GW848687X, a potent and selective prostaglandin EP1 receptor antagonist for the treatment of inflammatory pain."

Related Drugs and Biologics

1.	Prostaglandins
2.	Acids
3.	sodium 6- ((5- chloro- 2- (((4- chloro- 2- fluorophenyl)methyl)oxy)phenyl)methyl)- 2- pyridinecarboxylate