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A5B7 monoclonal antibody

an anti-carcinoembryonic antigen/CEA antibody used in radioimmunotherapy

Also Known As:

(131)I-labelled A5B7 mAb; 131I-A5B7 mAb; monoclonal antibody A5B7

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Serum Globulins: 553
      - Immunoglobulins: 30480
        Antibodies: 133716
        Monoclonal Antibodies: 56412
        A5B7 monoclonal antibody: 3
    - Immunoproteins: 43
      - Immunoglobulins: 30480
        Antibodies: 133716
        Monoclonal Antibodies: 56412
        A5B7 monoclonal antibody: 3
  - Globulins: 3062
    - Serum Globulins: 553
      - Immunoglobulins: 30480
        Antibodies: 133716
        Monoclonal Antibodies: 56412
        A5B7 monoclonal antibody: 3

Related Diseases

1.	Colorectal Neoplasms (Colorectal Cancer) 03/01/1991 - "Radioimmunoguided surgery (RIGS) using an anti-CEA (A5B7) monoclonal antibody has been assessed in 52 patients (43 primary excisions and nine second look procedures) undergoing surgery for colorectal carcinoma. " 11/01/1999 - "We have been investigating the use of cross-linked divalent (DFM) and trivalent (TFM) versions of the anti-carcinoembryonic antigen (CEA) monoclonal antibody A5B7 as possible alternatives to the parent forms (IgG and F(ab')2) which have been used previously in clinical radioimmunotherapy (RIT) studies in colorectal carcinoma. "
2.	Carcinoma (Carcinomatosis) 11/01/1996 - "The three-dimensional structure of the Fab fragment of the murine monoclonal antibody A5B7, which is specific for carcinoembryonic antigen (CEA) a protein expressed on carcinoma cell surfaces, has been determined. "

Related Drugs and Biologics

1.	Carcinoembryonic Antigen
2.	Immunoglobulin G (IgG)
3.	Proteins (Proteins, Gene)
4.	Immunoglobulin Fab Fragments

Related Therapies and Procedures

1.	Radioimmunotherapy