Autophagy-Related Protein-1 Homolog

A serine/threonine-protein kinase that functions in AUTOPHAGY in response to starvation. It acts on the PHOSPHATIDYLINOSITOL 3-KINASE complex PIK3C3 to regulate AUTOPHAGOSOME formation. It also functions as both a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) and is activated by AMPK, which it also negatively regulates.

Also Known As:

Serine-Threonine Protein Kinase ULK1; ULK1 Protein; Unc-51 Like Autophagy Activating Kinase 1; Unc-51-Like Kinase 1; Autophagy Related Protein 1 Homolog; Serine Threonine Protein Kinase ULK1; Unc 51 Like Autophagy Activating Kinase 1; Unc 51 Like Kinase 1

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Phosphotransferases: 42769
      - Phosphotransferases (Alcohol Group Acceptor)
        Protein Kinases: 9677
        Protein Serine-Threonine Kinases: 3588
        Autophagy-Related Protein-1 Homolog: 113
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Autophagy-Related Proteins: 555
    - Autophagy-Related Protein-1 Homolog: 113
  - Intracellular Signaling Peptides and Proteins: 32
    - Protein Serine-Threonine Kinases: 3588
      - Autophagy-Related Protein-1 Homolog: 113

Drosophila Atg1 protein

Bio-Agent Context: Research Results