KIOM 79

01/12/2009 - "These data show that KIOM-79 can prevent apoptosis in neuronal cells, AGEs accumulation in the retina, and retard the development of diabetic retinopathy."
06/16/2010 - "The purpose of this study was to investigate the protective effects of KIOM-79, a combination of four plant extracts, on retinal pericytes loss, which is one of the histopathological hallmarks of early diabetic retinopathy. "

01/01/2011 - "However, the administration of KIOM-79 delayed the development of diabetic cataracts and prevented LEC apoptosis (70%) through the inhibition of AGEs, NF-κB-activation and iNOS expression. "
08/09/2010 - "Therefore, KIOM-79 may provide a potential therapeutic approach for preventing diabetic complications, such as cataracts."
08/09/2010 - "To investigate the effects of KIOM-79 in preventing the development of diabetic complications, such as cataracts. "
08/09/2010 - "KIOM-79 is protective against lens opacity and protects HLE-B3 cells from the toxic effects of high glucose. "
08/09/2010 - "The inhibitory effects of KIOM-79 were assessed in a model of xylose-induced lens opacity and on changes mediated by high levels of glucose in human lens epithelial (HLE-B3) cells. "

09/25/2009 - "KIOM-79 could be beneficial for preventing of the development of diabetic complications such as nephropathy."
08/09/2010 - "Therefore, KIOM-79 may provide a potential therapeutic approach for preventing diabetic complications, such as cataracts."
08/09/2010 - "To investigate the effects of KIOM-79 in preventing the development of diabetic complications, such as cataracts. "

01/01/2011 - "In the present study, we investigated the effect of KIOM-79 on AGE accumulation and vascular inflammation in the aorta of Zucker diabetic fatty (ZDF) rats, a commonly used model of type 2 diabetes. "
01/12/2009 - "KIOM-79 retards the development of diabetic nephropathy in animal models of type 1 and type 2 diabetes. "
01/01/2011 - "KIOM-79, an 80% ethanolic extract obtained from parched Puerariae Radix, gingered Magnolia Cortex, Glycyrrhiza Radix and Euphorbia Radix, was investigated for its effects on the development of renal disease in Zucker diabetic fatty rats, an animal model of type 2 diabetes. "

01/01/2011 - "In the present study, we investigated the effect of KIOM-79 on AGE accumulation and vascular inflammation in the aorta of Zucker diabetic fatty (ZDF) rats, a commonly used model of type 2 diabetes. "
01/01/2011 - "These data suggest that KIOM-79 may prevent or retard the development of inflammation in diabetic vascular disease."