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pentabrominated diphenyl ether 100

structure in first source

Also Known As:

2,2',4,4',6-brominated diphenyl ether; BDE-100

Networked: 9 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Biphenyl Compounds: 7
        Polybrominated Biphenyls: 44
        pentabrominated diphenyl ether 100: 9
  - Halogenated Hydrocarbons: 42
    - Brominated Hydrocarbons: 1
      - Polybrominated Biphenyls: 44
        pentabrominated diphenyl ether 100: 9

Experts

1.	Chevrier, Jonathan: 2 articles (01/2017 - 10/2011)
2.	Hamdoun, Amro: 1 article (12/2020)
3.	Nicklisch, Sascha C T: 1 article (12/2020)
4.	Antignac, Jean-Philippe: 1 article (01/2020)
5.	Arveux, Patrick: 1 article (01/2020)
6.	Boutron-Ruault, Marie-Christine: 1 article (01/2020)
7.	Cano-Sancho, German: 1 article (01/2020)
8.	Cervenka, Iris: 1 article (01/2020)
9.	Kvaskoff, Marina: 1 article (01/2020)
10.	Mancini, Francesca Romana: 1 article (01/2020)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 01/01/2020 - "The analysis showed a non-linear inverse association for BDE-100 and BDE-153 and postmenopausal breast cancer risk; nevertheless, these findings were statistically significant only when the exposure was modeled as ng/L plasma (third vs. first quintile: OR = 0.42, 95%CI = 0.19-0.93 and OR = 0.42, 95%CI = 0.18-0.98, respectively) and not when modeled as ng/gr of lipids (OR = 0.58, 95%CI = 0.27-1.25 and OR = 0.53, 95%CI = 0.25-1.17). " 01/01/2019 - "Our findings provide no evidence that serum levels of BDE-47, BDE-100 or BDE-153 are associated with breast cancer risk. " 11/01/2018 - "In the adjusted univariate model for all cases, breast cancer risk was increased with both 2nd and 3rd tertiles versus the 1st tertile of BDE-47 level (OR 2.05 [95% CI 1.08-3.92]; 5.47 [2.96-10.11]) and BDE-209 level (2.48 [1.30-4.73]; 4.72 [2.52-8.83]) with trend (both P < 0.001) and with the 3rd tertile of BDE-28 level (2.83 [1.63-4.92]), BDE-99 (3.22 [1.85-5.60]), BDE-100 (5.45 [2.90-10.23]), BDE-138 (2.40 [1.37-4.20]), BDE-153 (1.74 [1.02-2.97]), BDE-154 (1.84 [1.05-3.22]), and ∑PBDE levels (1.83 [1.07-3.14]) but decreased with the 3rd tertile of BDE-71 level (0.38 [0.22-0.65]) with trend (all P < 0.01). "
2.	Tics (Tic) 12/01/2020 - "Recent results on the co-crystal structure of ABCB1 with the flame-retardant BDE-100 demonstrate that a diverse range of man-made and natural toxic molecules, hereafter termed transporter-interfering chemicals (TICs), can directly bind to SMTs and interfere with their function. "
3.	Weight Gain 08/01/2006 - "BDE-100 was most influential on nestling growth, being positively associated with size, weight gain, and food consumption. "
4.	Pheochromocytoma 04/01/2010 - "To investigate the neurotoxic potential of other environmentally relevant PBDEs and their metabolites, we examined and compared the acute effects of BDE-47, BDE-49, BDE-99, BDE-100, BDE-153, and several metabolites of BDE-47-6-OH-BDE-47 (and its methoxylated analog 6-MeO-BDE-47), 6 -OH-BDE-49, 5-OH-BDE-47, 3-OH-BDE-47, and 4 -OH-BDE-49--on intracellular Ca2+ concentration ([Ca2+]i), measured using the Ca2+-responsive dye Fura-2 in neuroendocrine pheochromocytoma (PC12) cells. "
5.	Cryptorchidism (Undescended Testes) 01/01/2017 - "In adjusted models, every 10-fold increase in the concentration of maternal hair BDE-99 [OR=2.53 (95% CI: 1.29, 4.95) or BDE-100 [OR=2.45 (95% CI: 1.31, 4.56)] was associated with more than a doubling in the risk of cryptorchidism. "

Related Drugs and Biologics

1.	hexabrominated diphenyl ether 153
2.	2,2',4,4'-tetrabromodiphenyl ether
3.	2,2',4,4',5-brominated diphenyl ether
4.	Lipids
5.	tribromodiphenyl ether 28
6.	Halogenated Diphenyl Ethers
7.	Fura-2 (Fura 2)
8.	Flame Retardants (Fire Retardants)
9.	Coloring Agents (Dyes)
10.	5-OH-BDE-47