hemoglobin Jambol

hyperunstable hemoglobin that causes severe hemolytic anemia; has mutation that leads to a deletion of 4 amino acid residues (Leu-Leu-Glu-Asn) at positions 105-108 and an insertion of 9 residues (Val-Pro-Ser-Val-Thr-Leu-Phe-Phe-Asp) at the same location, creating an abnormal elongated beta-chain of 151 amino acid residues

Also Known As:

Hb Jambol

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Hemoglobins: 37188
      - Abnormal Hemoglobins: 120
        hemoglobin Jambol: 2
  - Hemeproteins: 194
    - Globins: 2716
      - Hemoglobins: 37188
        Abnormal Hemoglobins: 120
        hemoglobin Jambol: 2

Experts

1.	Efremov, G D: 1 article (01/2007)
2.	Efremov, Georgi D: 1 article (01/2007)
3.	Petkov, G H: 1 article (01/2007)
4.	Plaseska-Karanfilska, D: 1 article (01/2007)
5.	Simjanovska, L: 1 article (01/2007)
6.	Stanojevic, E: 1 article (01/2007)

Related Diseases

1.	Hemolytic Anemia 01/01/2007 - "The second example is a new hyperunstable variant named Hb Jambol, found as a de novo mutation in a 2-year-old Bulgarian girl with severe hemolytic anemia. " 01/01/2007 - "Hb Jambol: a new hyperunstable hemoglobin causing severe hemolytic anemia."

Related Drugs and Biologics

1.	Hemoglobins (Hemoglobin)