Non-Receptor Type 11 Protein Tyrosine Phosphatase

A subtype of non-receptor protein tyrosine phosphatases that contain two SRC HOMOLOGY DOMAINS. Mutations in the gene for protein tyrosine phosphatase, non-receptor type 11 are associated with NOONAN SYNDROME.

Also Known As:

Protein Tyrosine Phosphatase, Non-Receptor Type 11; Phosphotyrosine Phosphatase Syp; Protein Tyrosine Phosphatase PTP3; Protein-Tyrosine-Phosphatase 2C; SHP-2 Protein-Tyrosine Phosphatase; SHP2 Phosphatase; SHPTP2; Shp-2 Tyrosine Phosphatase; Phosphatase, SHP2; Protein Tyrosine Phosphatase 2C; Protein Tyrosine Phosphatase, Non Receptor Type 11; Shp 2 Tyrosine Phosphatase; Tyrosine Phosphatase, Shp-2

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Esterases: 1574
      - Phosphoric Monoester Hydrolases: 7477
        Protein Tyrosine Phosphatases: 1685
        SH2 Domain-Containing Protein Tyrosine Phosphatases: 12
        Non-Receptor Type 11 Protein Tyrosine Phosphatase: 138
        Non-Receptor Protein Tyrosine Phosphatases: 4
        Non-Receptor Type 11 Protein Tyrosine Phosphatase: 138
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intracellular Signaling Peptides and Proteins: 32
    - Protein Tyrosine Phosphatases: 1685
      - SH2 Domain-Containing Protein Tyrosine Phosphatases: 12
        Non-Receptor Type 11 Protein Tyrosine Phosphatase: 138
      - Non-Receptor Protein Tyrosine Phosphatases: 4
        Non-Receptor Type 11 Protein Tyrosine Phosphatase: 138

mouse Ptpn11 protein

Bio-Agent Context: Research Results