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7- but- 2- ynyl- 9- (6- methoxy- pyridin- 3- yl)- 6- piperazin- 1- yl- 7,9- dihydro- purin- 8- one

is a dipeptidyl peptidase (DPP)-IV inhibitor; structure in first source

Also Known As:

ER-319711

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperazines: 26
    - 7-but-2-ynyl-9-(6-methoxy-pyridin-3-yl)-6-piperazin-1-yl-7,9-dihydro-purin-8-one: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - 7-but-2-ynyl-9-(6-methoxy-pyridin-3-yl)-6-piperazin-1-yl-7,9-dihydro-purin-8-one: 1

Experts

1.	Andoh, Akira: 1 article (06/2011)
2.	Bamba, Shigeki: 1 article (06/2011)
3.	Ban, Hiromitsu: 1 article (06/2011)
4.	Fujiyama, Yoshihide: 1 article (06/2011)
5.	Imaeda, Hirotsugu: 1 article (06/2011)
6.	Inatomi, Osamu: 1 article (06/2011)
7.	Kobori, Ayako: 1 article (06/2011)
8.	Sasaki, Masaya: 1 article (06/2011)
9.	Tsujikawa, Tomoyuki: 1 article (06/2011)

Related Diseases

1.	Colitis 06/01/2011 - "The disease activity index and colon length showed an amelioration of colitis in the DSS + ER-319711 group. " 06/01/2011 - "The mice were then given bromodeoxyuridine (BrdU) intraperitoneally 2 h before sacrifice on day 7. Twenty-six mice were divided into three groups: a vehicle group, a DSS-induced colitis group and a DSS-induced colitis treated with ER-319711 group. " 06/01/2011 - "The DPP-IV inhibitor ER-319711 has a proliferative effect on the colonic epithelium and a minimal effect in the amelioration of colitis."
2.	Body Weight (Weight, Body) 06/01/2011 - "The DSS + ER-319711 group had a decreased body weight transition. " 06/01/2011 - "The ER-319711 group had a significantly decreased body weight from days 1 to 3. The number of BrdU positive cells per crypt and the crypt height were increased in the ER-319711 group. "

Related Drugs and Biologics

1.	Dipeptidyl-Peptidase IV Inhibitors
2.	Bromodeoxyuridine (BrdU)