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ataluren

overrides nonsense stop translation signals to yield full-length proteins; may prove useful in treating cystic fibrosis and Duchenne muscular dystrophy
Also Known As:
PTC 124; PTC-124; PTC124
Networked: 28 relevant articles (2 outcomes, 12 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Elfring, Gary L: 4 articles (07/2014 - 04/2007)
2. Barth, Jay: 3 articles (07/2014 - 01/2013)
3. Peltz, Stuart W: 3 articles (07/2014 - 04/2007)
4. Reha, Allen: 3 articles (09/2013 - 11/2010)
5. Northcutt, Valerie J: 3 articles (01/2013 - 04/2007)
6. Miller, Langdon L: 3 articles (11/2010 - 04/2007)
7. Hirawat, Samit: 3 articles (11/2010 - 04/2007)
8. Welch, Ellen M: 2 articles (07/2014 - 04/2007)
9. Ajayi, Temitayo: 2 articles (07/2014 - 11/2010)
10. Rowe, Steven M: 2 articles (07/2014 - 01/2009)

Related Diseases

1. Cystic Fibrosis (Mucoviscidosis)
2. Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker)
3. Propionic Acidemia
4. Retinal Degeneration
5. Acute Kidney Injury (Acute Renal Failure)

Related Drugs and Biologics

1. Nonsense Codon (Nonsense Mutation)
2. Aminoglycosides
3. Tobramycin (Nebcin)
4. Proteins (Proteins, Gene)
5. Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)
6. Biological Markers (Surrogate Marker)
7. Dystrophin
8. 6-propylchromone-2-carboxylic acid (PCCA)
9. ataluren
10. Retinaldehyde (Retinal)

Related Therapies and Procedures

1. Oral Administration