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SC1 compound

used to propagate murine ES cells in an undifferentiated and pluripotent state; structure in first source

Also Known As:

pluripotin

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrazoles: 61
      - SC1 compound: 2
  - Pyrimidines: 510
    - SC1 compound: 2

Experts

1.	Alley, Michael C: 1 article (01/2013)
2.	Covell, David G: 1 article (01/2013)
3.	Divelbiss, Raymond D: 1 article (01/2013)
4.	Hite, Karen M: 1 article (01/2013)
5.	Hollingshead, Melinda G: 1 article (01/2013)
6.	Mertins, Susan D: 1 article (01/2013)
7.	Monks, Anne: 1 article (01/2013)
8.	Niederhuber, John E: 1 article (01/2013)
9.	Salomon, David S: 1 article (01/2013)
10.	Scudiero, Dominic A: 1 article (01/2013)

Related Diseases

1.	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/01/2023 - "Treatment with pluripotin curbed the progression of acute myeloid leukemia (AML) in multiple in vivo models including patient-derived primary AML cells in mouse xenotransplants. "
2.	Neoplasms (Cancer) 01/01/2013 - "The seven tumor lines of the NCI60 colon subpanel were exposed to SC-1 (pluripotin), a dual kinase and GTPase inhibitor that promotes self-renewal, and then examined for tumorigenicity under limiting dilution conditions and clonogenic activity in soft agar. "

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