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N(3)-(2-fluoroethyl)thymidine
structure in first source
Also Known As:
(18F)NFT202; N(3)-(2-(18F)fluoroethyl)thymidine; N3-(2-fluoroethyl)thymidine; NFT 202; NFT-202; NFT202
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyrimidines: 510
Pyrimidine Nucleosides: 50
Thymidine: 4460
N(3)-(2-fluoroethyl)thymidine: 1
Nucleic Acids, Nucleotides, and Nucleosides: 1
Nucleosides: 6847
Pyrimidine Nucleosides: 50
Thymidine: 4460
N(3)-(2-fluoroethyl)thymidine: 1
Deoxyribonucleosides: 34
Thymidine: 4460
N(3)-(2-fluoroethyl)thymidine: 1
Experts
1.
Fujibayashi, Yasuhisa
: 1 article (08/2006)
2.
Gogami, Akie
: 1 article (08/2006)
3.
Hayashi, Akio
: 1 article (08/2006)
4.
Toyohara, Jun
: 1 article (08/2006)
Related Diseases
1.
Lewis Lung Carcinoma
08/01/2006 - "
Whereas [(18)F]NFT202 did not accumulate in mouse Lewis lung carcinoma tumors, 3'-[(18)F]3'-fluoro-3'-deoxythymidine ([(18)F]FLT) showed significantly high uptake.
"
2.
Neoplasms (Cancer)
08/01/2006 - "
We therefore conclude that [(18)F]NFT202 is not a suitable PET ligand for imaging tumor cell proliferation.
"
08/01/2006 - "
[(14)C]NFT202 was not effectively incorporated into the DNA fraction and was indeed washed out from tumor cells.
"
08/01/2006 - "
However, the net in vitro tumor cell uptake of [(14)C]NFT202 was lower than that of [2-(14)C]3'-fluoro-3'-deoxythymidine.
"
08/01/2006 - "
Whereas [(18)F]NFT202 did not accumulate in mouse Lewis lung carcinoma tumors, 3'-[(18)F]3'-fluoro-3'-deoxythymidine ([(18)F]FLT) showed significantly high uptake.
"
Related Drugs and Biologics
1.
Thymidine
2.
Ligands
3.
DNA (Deoxyribonucleic Acid)