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Description: vanilloid receptor subunit 1 (TRPV1) antagonist; structure in first source
Also Known As:| 1. | Pain (Aches)
10/01/2006
- "Taken together, these findings demonstrate that compound H-Arg-15-15C is a channel blocker of TRPV1 with analgesic and anti-inflammatory activity in vivo at clinically useful doses and substantiate the tenet that TRPV1 plays an important role in the etiology of chronic inflammatory pain"
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| 2. | Hyperalgesia
10/01/2006
- "Notably, administration of compound H-Arg-15-15C prevented the irritant activity of a local administration of capsaicin and formalin and reversed the thermal hyperalgesia evoked by injection of complete Freund's adjuvant"
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| 2 Diseases and 1 more articles analyzed in the Research Interface, order at left... | |
| 1. | Freund's Adjuvant
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| 2. | Formaldehyde (Formol)
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| 3. | Capsaicin (Zostrix)
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| 3 Drugs and Important Bio-Agents and 1 more articles analyzed in the Research Interface, order at left... | |
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