3- hydroxy- 13- amino- 13,17- secoandrostan- 17- oic- 13,17- lactam p-bis(2-chloroethyl)amino phenyl acetate

04/01/2005 - "A preclinical survey on the efficacy of lactandrate in the treatment of colon carcinoma."
04/01/2005 - "Preclinical research supports the high in vitro and in vivo antitumour potential of lactandrate against colon carcinoma. "

04/01/2005 - "Lactandrate displayed a satisfactory activity against the 9 human colon cancer cell lines, inducing significant growth inhibition and cytotoxicity. "
04/01/2005 - "Lactandrate induced antiproliferative activity against colon cancer cell lines linearly correlated with the carcinoembryonic antigen (CEA) production. "
04/01/2005 - "The cytostatic and cytotoxic activity of lactandrate were evaluated in vitro against 9 human colon adenocarcinoma cell lines. "
11/18/2006 - "We tested two alkylating homo-aza-steroid esters, lactandrate and lactestoxate, for antineoplastic activity against colon adenocarcinoma in vitro and in vivo. "
04/01/2005 - "We tested lactandrate, an alkylating ester of D-lactam androsterone, for antineoplastic activity against colon adenocarcinoma in vitro and in vivo. "

05/01/2006 - "An androsterone D-lactam steroidal ester, the 3beta-hydroxy-13alpha-amino-13,17-seco- 5alpha-androstan-17-oic-13,17-lactam, p-bis(2-chloroethyl)amino phenyl acetate (lactandrate) was synthesized and tested for antitumor activity against six human breast cancer cell lines in vitro and against two murine and one xenograft mammary tumors in vivo. "

05/01/2006 - "Lactandrate produced important anticancer activity on breast cancer in vitro and in vivo. "
05/01/2006 - "Lactandrate: a D-homo-aza-androsterone alkylator in the treatment of breast cancer."
05/01/2006 - "An androsterone D-lactam steroidal ester, the 3beta-hydroxy-13alpha-amino-13,17-seco- 5alpha-androstan-17-oic-13,17-lactam, p-bis(2-chloroethyl)amino phenyl acetate (lactandrate) was synthesized and tested for antitumor activity against six human breast cancer cell lines in vitro and against two murine and one xenograft mammary tumors in vivo. "

05/01/2006 - "In vitro testing of lactandrate cytostatic and cytotoxic activity was performed on T47D, MCF7, MDA-MB-231, BT-549, Hs578T, MDA-MB-435 breast adenocarcinoma human cell lines. "