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6- N,N- bis(2,2,2- trifluoroethyl)amino- 4- trifluoromethylquinolin- 2(1H)- one

an androgen receptor modulator; structure in first source

Also Known As:

LGD 2226; LGD-2226; LGD2226

Networked: 1 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolines: 146
      - Quinolones: 2938
        6-N,N-bis(2,2,2-trifluoroethyl)amino-4-trifluoromethylquinolin-2(1H)-one: 1
      - Aminoquinolines: 29
        6-N,N-bis(2,2,2-trifluoroethyl)amino-4-trifluoromethylquinolin-2(1H)-one: 1

Experts

1.	Negro-Vilar, A: 1 article (03/2002)
2.	Rosen, J: 1 article (03/2002)

Related Diseases

1.	Hypogonadism (Hypergonadotropic Hypogonadism) 03/01/2002 - "In recent studies, we have used a skeletally mature orchiectomized (ORX) male rat as an animal model of male hypogonadism for assessing the efficacy of LGD2226, a nonsteroidal, non-aromatizable, and non-5alpha-reducible SARM. "
2.	Bone Resorption 03/01/2002 - "Biochemical markers of bone turnover revealed an early increase of bone resorption in androgen-deficient rats that was repressed in ORX animals treated with the oral SARM, LGD2226, during a 4-month treatment period. "

Related Drugs and Biologics

1.	Biomarkers (Surrogate Marker)
2.	Androgens