dehydrosilybin

inhibits cytochrome P450 1A1 catalytic activity; structure in first source

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

1.	Hepatocellular Carcinoma (Hepatoma) 03/01/2006 - "Silybin and dehydrosilybin inhibit cytochrome P450 1A1 catalytic activity: a study in human keratinocytes and human hepatoma cells." 03/01/2006 - "This study addressed the effect of silybin and dehydrosilybin on the activity of cytochrome P450 isoform CYP1A1 in human keratinocytes (HaCaT) and human hepatoma cells (HepG2). "
2.	Ischemia 12/01/2010 - "We infer that the apparent uncoupler-like activity of dehydrosilybin is the basis of its ROS modulation effect in neonatal rat cardiomyocytes and leads us to propose a hypothesis on natural ischemia preconditioning by dietary polyphenols."

1.	Protein Isoforms (Isoforms)
2.	Cytochrome P-450 CYP1A1 (CYP1A1)
3.	Cytochrome P-450 Enzyme System (Cytochrome P450)
4.	Silybin (Lagosa)
5.	Polyphenols