|1.||Yu, Chang-Xi: 3 articles (01/2015 - 05/2012)|
|2.||Liu, Ming: 3 articles (01/2015 - 05/2012)|
|3.||Yang, Jian: 3 articles (01/2015 - 05/2012)|
|4.||Xu, Ying: 3 articles (01/2015 - 05/2012)|
|5.||Chi, De-biao: 3 articles (09/2009 - 09/2003)|
|6.||Qiu, Hong-Qiang: 2 articles (01/2015 - 05/2012)|
|7.||Lei, Lin-sheng: 2 articles (09/2009 - 09/2003)|
|8.||Wang, Yong-Xiang: 1 article (01/2015)|
|9.||Jin, Gui-Lin: 1 article (01/2015)|
|10.||Li, Su-Ping: 1 article (01/2015)|
|1.||Neuralgia (Stump Neuralgia)
01/01/2015 - "This study demonstrates that 3α-HSOR is an important molecular target of koumine for alleviating neuropathic pain. "
01/01/2015 - "Koumine enhances spinal cord 3α-hydroxysteroid oxidoreductase expression and activity in a rat model of neuropathic pain."
01/01/2014 - "Koumine treatment of diabetic rats decreased neuropathic pain behavior as early as after the first administration. "
01/01/2015 - "Koumine may prove a promising compound for the development of novel analgesic agents effective against intractable neuropathic pain."
01/01/2015 - "Our results confirm that koumine alleviates neuropathic pain in rats with CCI by enhancing 3α-HSOR mRNA expression and bioactivity in the SC. "
09/01/2003 - "To study the apoptosis-inducing effect of koumine on human colon adenocarcinoma LoVo cells in vitro. "
09/01/2003 - "[Study of koumine-induced apoptosis of human colon adenocarcinoma LoVo cells in vitro]."
07/01/2007 - "To investigate the cell biological mechanism of koumine-induced apoptosis of human colonic adenocarcinoma cells. "
07/01/2007 - "[Koumine-induced apoptosis of human colonic adenocarcinoma cells: the cell biological mechanism]."
|3.||Psoriasis (Pustulosis Palmaris et Plantaris)
05/01/2005 - "To study the therapeutic effects of koumine on psoriasis in mouse models. "
05/01/2005 - "[Therapeutic effects of koumine on psoriasis: an experimental study in mice]."
05/01/2005 - "The therapeutic effect of koumine against psoriasis is related to the inhibition of epidermal cell proliferation, promoting the formation of granular cells and decreasing the serum level of IL-2."
|4.||Diabetic Neuropathies (Diabetic Neuropathy)
01/01/2014 - "In the current study, we examined the potential effects of koumine, a Gelsemium elegans Benth alkaloid, using a rat model of diabetic neuropathy. "
01/01/2014 - "These findings encourage the use of koumine in the treatment of diabetic neuropathy."
01/01/2014 - "Anti-allodynic and neuroprotective effects of koumine, a Benth alkaloid, in a rat model of diabetic neuropathy."
|1.||Analgesics (Analgesic Drugs)
|4.||Acetic Acid (Vinegar)
|5.||Sodium Chloride (Saline Solution)
|6.||Messenger RNA (mRNA)
|7.||Morphine (MS Contin)