|1.||Demarquay, Danièle: 1 article (09/2006)|
|2.||Ferrandis, Eric: 1 article (09/2006)|
|3.||Roubert, Pierre: 1 article (09/2006)|
|4.||Attoub, Samir: 1 article (09/2006)|
|5.||Nguyen, Quang-Dé: 1 article (09/2006)|
|6.||Bracke, Mark: 1 article (09/2006)|
|7.||Huchet, Marion: 1 article (09/2006)|
|8.||Wright, John: 1 article (09/2006)|
|9.||Prévost, Grégoire P: 1 article (09/2006)|
|10.||Chaumeron, Sophie: 1 article (09/2006)|
09/15/2006 - "BIM-46174 inhibits the growth of a large panel of human cancer cell lines, including anticancer drug-resistant cells. "
09/15/2006 - "Exposure of cancer cells to BIM-46174 leads to caspase-3-dependent apoptosis and poly(ADP-ribose) polymerase cleavage. "
09/15/2006 - "The growth rate of human tumor xenografts in athymic mice is significantly reduced after administration of BIM-46174 combined with either cisplatin, farnesyltransferase inhibitor, or topoisomerase inhibitors. "
09/15/2006 - "BIM-46174 prevents the heterotrimeric G-protein signaling linked to several GPCRs mediating (a) cyclic AMP generation (Galphas), (b) calcium release (Galphaq), and (c) cancer cell invasion by Wnt-2 frizzled receptors and high-affinity neurotensin receptors (Galphao/i and Galphaq). "
|4.||GTP-Binding Proteins (G-Protein)
|5.||Neurotensin Receptors (Neurotensin Receptor)
|6.||Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)
|9.||Cyclic AMP (AMP, Cyclic)
|1.||Heterologous Transplantation (Xenotransplantation)