|1.||Ng, Tzi Bun: 13 articles (01/2014 - 07/2005)|
|2.||Ng, T B: 13 articles (07/2010 - 12/2000)|
|3.||Wong, Jack H: 8 articles (07/2010 - 02/2003)|
|4.||Lin, Peng: 6 articles (02/2010 - 10/2007)|
|5.||Wong, Jack Ho: 5 articles (08/2010 - 07/2005)|
|6.||Wang, Hexiang: 4 articles (01/2014 - 10/2009)|
|7.||Ngai, Patrick H K: 4 articles (07/2010 - 11/2003)|
|8.||Das, Kalyan: 3 articles (03/2013 - 12/2005)|
|9.||Arnold, Eddy: 3 articles (03/2013 - 12/2005)|
|10.||Hartman, Tracy L: 3 articles (01/2012 - 09/2005)|
|1.||Acquired Immunodeficiency Syndrome (AIDS)
12/01/2005 - "In the treatment of AIDS, the efficacy of all drugs, including non-nucleoside inhibitors (NNRTIs) of HIV-1 reverse transcriptase (RT), has been limited by the rapid appearance of drug-resistant viruses. "
04/27/1999 - "Combined inhibition of HIV-1 reverse transcriptase and protease has significantly improved the treatment of AIDS. "
03/01/2000 - "Since the Human Immunodeficiency Virus Type 1 (HIV-1) was identified as the etiologic agent of the Acquired Immune Deficiency Syndrome (AIDS), the HIV-1 reverse transcriptase (RT) has been the subject of intensive study. "
03/26/2015 - "The HIV-1 Reverse Transcriptase (RT) is a validated and deeply explored biological target for the treatment of AIDS. "
02/01/2012 - "Combinations of nucleoside and non-nucleoside inhibitors (NNRTIs) of HIV-1 reverse transcriptase (RT) are widely used in anti-AIDS therapies. "
01/01/2013 - "The HIV-1 reverse transcriptase (RT) is one of the most attracting targets for the development of early phase infection inhibitors. "
01/01/2010 - "These results indicate that specific 3'-azido or acyclic nucleoside analog inhibitors of HIV-1 reverse transcriptase (RT) also block XMRV infection with comparable efficacy in vitro. "
04/04/2008 - "Reduced dNTP binding affinity of 3TC-resistant M184I HIV-1 reverse transcriptase variants responsible for viral infection failure in macrophage."
01/01/2008 - "The high replication rate and the error-prone nature of HIV-1 reverse transcriptase create a diverse viral quasispecies throughout infection. "
08/01/2007 - "The goal was to analyze and compare HIV-1 reverse transcriptase (RT) and protease (PR) genes of untreated individuals with chronic and recent infections. "
02/19/1999 - "The specificity of anti-tat mAbs in abolishing the transactivating potential of extracellular tat is documented by studies with mAbs to HIV-1 reverse transcriptase, or to a human mammary cancer protein. "
09/01/2009 - "It inhibited proliferation of HepG2 and MCF cancer cells with an IC(50) of 6.4 microM and 1.8 microM, and the activity of HIV-1 reverse transcriptase with an IC(50) of 3.2 microM. "
07/01/2005 - "Sesquin, a potent defensin-like antimicrobial peptide from ground beans with inhibitory activities toward tumor cells and HIV-1 reverse transcriptase."
01/01/2014 - "Banana lectins have the potential for inhibiting HIV-1 reverse transcriptase activity, suppressing cancer cell proliferation and stimulating macrophage activities. "
08/01/2010 - "Purification and characterization of a Laccase with inhibitory activity toward HIV-1 reverse transcriptase and tumor cells from an edible mushroom (Pleurotus cornucopiae)."
|4.||AIDS Dementia Complex
04/13/2001 - "HIV-1 reverse transcriptase sequence in plasma and cerebrospinal fluid of patients with AIDS dementia complex treated with Abacavir."
04/13/2001 - "To assess HIV-1 RNA levels and the relationship between HIV-1 reverse transcriptase (RT) genotype from plasma and cerebrospinal fluid (CSF) during treatment with abacavir (Ziagen, ABC) or placebo in combination with stable background therapy (SBG) in subjects with AIDS dementia complex (ADC) (study CNA3001). "
|5.||Hepatocellular Carcinoma (Hepatoma)
01/15/2010 - "The haemagglutinin exhibited a weak mitogenic activity toward mouse splenocytes, a stronger anti-proliferative activity than Con A toward HepG2 (human hepatoma) cells and inhibited >80% of HIV-1 reverse transcriptase inhibitory activity at 3.3 micromol L(-1). "
10/01/2009 - "The HA exhibited some antiproliferative activity towards hepatoma (HepG2) cells and inhibited HIV-1 reverse transcriptase (IC50=10 microM). "
07/01/2010 - "It inhibited HIV-1 reverse transcriptase and proliferation of hepatoma HepG2 cells and breast cancer MCF7 cells with an IC50 of 0.65 microM, 1.4 microM, and 4.2 microM, respectively, indicating that it is also an antipathogenic protein."
10/01/2009 - "The lectin potently inhibited HIV-1 reverse transcriptase with an IC50 of 0.28 microM and proliferation of both hepatoma HepG2 and breast cancer MCF-7 cells with an IC50 of approx. "
06/01/2009 - "The lectin also inhibited proliferation of leukemia (L1210) cells and hepatoma (HepG2) cells and the activity of HIV-1 reverse transcriptase. "
|2.||RNA (Ribonucleic Acid)
|5.||DNA (Deoxyribonucleic Acid)
|6.||DNA-Directed DNA Polymerase (Polymerases, DNA)
|9.||Proteins (Proteins, Gene)
|1.||Highly Active Antiretroviral Therapy (HAART)
|2.||Drug Therapy (Chemotherapy)