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isoglobotrihexosylceramide

structure in first source

Also Known As:

iGb3 ceramide

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Bonrouhi, Mahnaz: 1 article (09/2012)
2.	Cerundolo, Vincenzo: 1 article (09/2012)
3.	Dyson, Julian: 1 article (09/2012)
4.	Gröne, Hermann-Josef: 1 article (09/2012)
5.	Jennemann, Richard: 1 article (09/2012)
6.	Lehuen, Agnes: 1 article (09/2012)
7.	Luckow, Bruno: 1 article (09/2012)
8.	Malle, Ernst: 1 article (09/2012)
9.	Müthing, Johannes: 1 article (09/2012)
10.	Platt, Frances M: 1 article (09/2012)

Related Diseases

1.	Neoplasms (Cancer) 08/01/2006 - "Based on genetic data and cellular immunological assays, we propose a neutral glycosphingolipid isoglobotrihexosylceramide, iGb3, as one of the candidates recognized by NKT cells under patho-physiological conditions such as cancer and auto-immune disease. "
2.	Infections 10/01/2006 - "As for natural killer T cells, the recent identification of one endogenous ligand, isoglobotrihexosylceramide, and of a family of bacterial agonists is an important advance for understanding their thymic selection and their role during infections."
3.	Immune System Diseases (Immune Disorders) 08/01/2006 - "Based on genetic data and cellular immunological assays, we propose a neutral glycosphingolipid isoglobotrihexosylceramide, iGb3, as one of the candidates recognized by NKT cells under patho-physiological conditions such as cancer and auto-immune disease. "
4.	Fabry Disease (Fabry's Disease) 09/15/2012 - "Isoglobotrihexosylceramide (iGb3) has been implicated as this endogenous selecting ligand and recently suggested to control overstimulation and deletion of iNKT cells in α-galactosidase A-deficient (αGalA(-/-)) mice (human Fabry disease), which accumulate isoglobosides and globosides. "

Related Drugs and Biologics

1.	Ligands
2.	Glycosphingolipids
3.	Globosides
4.	Galactosidases