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geodiamolide H

has antineoplastic activity; isolated from Geodia corticostylifera; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Cyclic Peptides: 530
    - Depsipeptides: 297
      - geodiamolide H: 1
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Cyclic Peptides: 530
    - Depsipeptides: 297
      - geodiamolide H: 1

Experts

1.	Bisson, Letícia F: 1 article (09/2008)
2.	Freitas, Vanessa M: 1 article (09/2008)
3.	Jaeger, Ruy G: 1 article (09/2008)
4.	Machado-Santelli, Gláucia M: 1 article (09/2008)
5.	Rangel, Marisa: 1 article (09/2008)

Related Diseases

1.	Neoplasms (Cancer) 09/01/2008 - "We are investigating effects of the depsipeptide geodiamolide H, isolated from the Brazilian sponge Geodia corticostylifera, on cancer cell lines grown in 3D environment. "
2.	Breast Neoplasms (Breast Cancer) 09/01/2008 - "As shown previously geodiamolide H disrupts actin cytoskeleton in both sea urchin eggs and breast cancer cell monolayers. " 09/01/2008 - "The geodiamolide H, derived from Brazilian sponge Geodia corticostylifera, regulates actin cytoskeleton, migration and invasion of breast cancer cells cultured in three-dimensional environment."

Related Drugs and Biologics

1.	Depsipeptides