alphastatin

01/01/2009 - "Immunohistochemical studies of tumor tissues revealed decreased microvessel density in alphastatin-treated animals as compared with controls. "
07/14/2006 - "Immunohistochemical studies of tumor tissues revealed decreased micro vessel density in alphastatin-treated animals as compared with controls. "
12/22/2020 - "alphastatin-C is an efficient new antiangiogenic FGF-associated agent in vitro, it is an inhibitor of embryonic and tumor vascularization in vivo while, it is an arteriogenic agent. "
01/01/2009 - "Alphastatin shows potent antiangiogenic properties in nude mice,which might be closely associated with down-regulation of tumor endothelial cells SPK activity."
01/01/2009 - "Alphastatin significantly inhibited tumor endothelial cells SPK activity. "

11/01/2023 - "The aim of the present study was to construct an ADSC‑mediated alphastatin targeted delivery system and investigate its effects on angiogenesis in glioma. "
03/01/2013 - " We found that the transduced glioma cells sustainedly secreted alphastatin, which did not affect the proliferative ability of the glioma cells. "
05/01/2011 - "This study was to investigate whether local sustained long-term expression of alphastatin could serve to diminish tumor growth of a human xenograft glioma model. "
11/01/2023 - "Adipose‑derived stem cell‑mediated alphastatin targeting delivery system inhibits angiogenesis and tumor growth in glioma."
03/01/2013 - "Inhibition of xenograft human glioma tumor growth by lentivirus-mediated gene transfer of alphastatin."

07/14/2006 - "Downregulating ECs SPK activity may be one of the mechanisms that alphastatin inhibits gastric cancer angiogenesis. "
07/14/2006 - "Alphastatin might be a useful and relatively nontoxic adjuvant therapy in the treatment of gastric cancer."
01/01/2009 - "To explore the effect and mechanism of alphastatin on tumor angiogenesis in nude mice bearing human gastric cancer xenografts. "
01/01/2009 - "[Alphastatin inhibits tumor angiogenesis in nude mice bearing human gastric cancer xenografts]."
01/01/2012 - "To explore the differential protein expression profile in EC304 gastric cancer cells induced by alphastatin. "

01/15/2004 - "Tumors from mice receiving daily injections of alphastatin for 12 days exhibited large areas of intravascular disruption and thrombosis with substantial cellular necrosis. "

01/15/2004 - "Tumors from mice receiving daily injections of alphastatin for 12 days exhibited large areas of intravascular disruption and thrombosis with substantial cellular necrosis. "