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nicotiflorin

is a single component extracted from traditional Chinese medicine Flos Carthami; structure in first source
Networked: 4 relevant articles (1 outcomes, 2 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Guo, Meili: 2 articles (09/2006 - 08/2006)
2. Zhang, Ge: 2 articles (09/2006 - 08/2006)
3. Xu, Xiongfei: 2 articles (09/2006 - 08/2006)
4. Li, Runping: 2 articles (09/2006 - 08/2006)
5. Li, Quan: 2 articles (09/2006 - 08/2006)
6. Nakayama, Mao: 1 article (01/2011)
7. Aihara, Makoto: 1 article (01/2011)
8. Tomita-Yokotani, Kaori: 1 article (01/2011)
9. Iwashina, Tsukasa: 1 article (01/2011)
10. Araie, Makoto: 1 article (01/2011)

Related Diseases

1. Multi-Infarct Dementia (Dementia, Multi Infarct)
04/01/2007 - "These results suggest that Nicotiflorin has protective effects on reducing memory dysfunction, energy metabolism failure and oxidative stress in multi-infarct dementia model rats."
04/01/2007 - "Protective effects of Nicotiflorin on reducing memory dysfunction, energy metabolism failure and oxidative stress in multi-infarct dementia model rats."
04/01/2007 - "The present study aimed to determine whether Nicotiflorin, a natural flavonoid extracted from coronal of Carthamus tinctorius, has a protective effect on cerebral multi-infarct dementia in rats. "
04/01/2007 - "2,3,5-triphenyltetrazolium chloride (TTC) staining showed that infarct volume of each Nicotiflorin administration group was much smaller than that of vehicle-treated multi-infarct dementia group, and hematoxylin and eosin (HE) staining showed that histopathological abnormalities of each Nicotiflorin group were also much lighter than that of vehicle-treated multi-infarct dementia group. "
04/01/2007 - "Each Nicotiflorin group showed much better spatial memory performance in Morris water maze tests and eight-arm radial maze task compared with the vehicle-treated multi-infarct dementia group, significantly attenuated the elevation of lactic acid and malondialdehyde (MDA) contents and the decrease in lactate dehydrogenase (LDH), Na(+)K(+)ATPase, Ca(2+)Mg(2+)ATPase and superoxide dismutase (SOD) activity in the brain tissue which was composed of striatum, cortex and hippocampus of the ischemia hemisphere at day 3 after ischemia operation. "
2. Ischemia
3. Brain Ischemia (Cerebral Ischemia)
4. Anoxia (Hypoxia)

Related Drugs and Biologics

1. Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)
2. Lactic Acid
3. Glutamic Acid (Glutamate)
4. Ca(2+) Mg(2+)-ATPase
5. Superoxide Dismutase
6. Rutin (Rutoside)
7. Messenger RNA (mRNA)
8. Malondialdehyde (Propanedial)
9. L-Lactate Dehydrogenase (Lactate Dehydrogenase)
10. Hematoxylin (Haematoxylon)