Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels

A subgroup of cyclic nucleotide-regulated ION CHANNELS of the superfamily of pore-loop cation channels that are opened by hyperpolarization rather than depolarization. The ion conducting pore passes SODIUM, CALCIUM, and POTASSIUM cations with a preference for potassium.

Also Known As:

HCN Pacemaker Channels; HCN1 Channel; HCN2 Channel; HCN2 Potassium Channel; HCN3 Channel; HCN4 Channel; Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 2; Hyperpolarization Cyclic-Nucleotide Gated Cation Channel 1; Hyperpolarization Cyclic-Nucleotide Gated Cation Channel 3; Hyperpolarization Cyclic-Nucleotide Gated Cation Channel 4; Hyperpolarization-Activated Cation Channel; I(h) Cation Channels; I(h) Channels; Ih Cation Channels; Potassium-Sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 2; Cation Channel, Hyperpolarization-Activated; Cation Channels, Ih; Channel, HCN1; Channel, HCN2; Channel, HCN2 Potassium; Channel, HCN3; Channel, HCN4; Channel, Hyperpolarization-Activated Cation; Channels, HCN Pacemaker; Channels, Ih Cation; Hyperpolarization Activated Cation Channel; Hyperpolarization Activated Cyclic Nucleotide Gated Channels; Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 2; Hyperpolarization Cyclic Nucleotide Gated Cation Channel 1; Hyperpolarization Cyclic Nucleotide Gated Cation Channel 3; Hyperpolarization Cyclic Nucleotide Gated Cation Channel 4; Hyperpolarization Cyclic Nucleotide Gated Ion Channels; Pacemaker Channels, HCN; Potassium Channel, HCN2; Potassium Sodium Hyperpolarization Activated Cyclic Nucleotide Gated Channel 2; Hyperpolarization Cyclic-Nucleotide Gated Ion Channels

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Carrier Proteins: 12999
    - Membrane Transport Proteins: 589
      - Ion Channels: 6731
        Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels: 96
  - Membrane Proteins: 10078
    - Membrane Glycoproteins: 2252
      - Ion Channels: 6731
        Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels: 96
    - Membrane Transport Proteins: 589
      - Ion Channels: 6731
        Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels: 96

rat HCN4 protein

Bio-Agent Context: Research Results