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degalactotigonin

cytotoxic compound from the whole plant of Solanum nigrum; structure in first source

Also Known As:

desgalactotigonin

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycosides: 2119
  - Saponins: 2867
    - degalactotigonin: 3
Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - degalactotigonin: 3

Experts

1.	Chen, Linbao: 1 article (12/2020)
2.	Chu, Chuanmin: 1 article (12/2020)
3.	Cui, Xingang: 1 article (12/2020)
4.	Hong, Tianyu: 1 article (12/2020)
5.	Jiang, Ning: 1 article (12/2020)
6.	Wang, Chao: 1 article (12/2020)
7.	Wang, Yuning: 1 article (12/2020)
8.	Zhang, Jing: 1 article (12/2020)
9.	Zheng, Jingcun: 1 article (12/2020)
10.	Zhu, Jiangbo: 1 article (12/2020)

Related Diseases

1.	Osteosarcoma (Osteogenic Sarcoma) 01/01/2018 - "Degalactotigonin, a Natural Compound from Solanum nigrum L., Inhibits Growth and Metastasis of Osteosarcoma through GSK3β Inactivation-Mediated Repression of the Hedgehog/Gli1 Pathway."
2.	Pancreatic Neoplasms (Pancreatic Cancer) 01/01/2018 - "Degalactotigonin, a Steroidal Glycoside from Solanum nigrum, Induces Apoptosis and Cell Cycle Arrest via Inhibiting the EGFR Signaling Pathways in Pancreatic Cancer Cells."
3.	Neoplasms (Cancer) 01/01/2018 - "Only degalactotigonin (1) showed potent cytotoxicity against these cancer cell lines. "
4.	Neoplasm Metastasis (Metastasis) 01/01/2018 - "Degalactotigonin, a Natural Compound from Solanum nigrum L., Inhibits Growth and Metastasis of Osteosarcoma through GSK3β Inactivation-Mediated Repression of the Hedgehog/Gli1 Pathway."
5.	Renal Cell Carcinoma (Grawitz Tumor) 12/01/2020 - "The natural extract degalactotigonin exerts antitumor effects on renal cell carcinoma cells through repressing YAP."

Related Drugs and Biologics

1.	Glycosides