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2'-C-methylcytidine

structure in first source

Also Known As:

2'-C-methyl-cytidine

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidine Nucleosides: 50
      - Cytidine: 535
        2'-C-methylcytidine: 7
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleosides: 6847
  - Pyrimidine Nucleosides: 50
    - Cytidine: 535
      - 2'-C-methylcytidine: 7
  - Ribonucleosides: 49
    - Cytidine: 535
      - 2'-C-methylcytidine: 7

Experts

1.	Neyts, Johan: 2 articles (01/2016 - 11/2013)
2.	Rocha-Pereira, Joana: 2 articles (01/2016 - 11/2013)
3.	Pan, Qiuwei: 1 article (10/2017)
4.	Peppelenbosch, Maikel P: 1 article (10/2017)
5.	Qu, Changbo: 1 article (10/2017)
6.	Wang, Wenshi: 1 article (10/2017)
7.	Xu, Lei: 1 article (10/2017)
8.	Yin, Yuebang: 1 article (10/2017)
9.	Kolawole, Abimbola O: 1 article (01/2016)
10.	Verbeken, Eric: 1 article (01/2016)

Related Diseases

1.	Diarrhea 01/01/2016 - "Using the MNV, we previously discovered that the viral polymerase inhibitor 2'-C-methylcytidine (2CMC) is able to protect against diarrhea and mortality in mice when used prophylactically and to block the transmission of MNV between mice. " 11/01/2013 - "The viral polymerase inhibitor 2'-C-methylcytidine inhibits Norwalk virus replication and protects against norovirus-induced diarrhea and mortality in a mouse model." 11/02/2006 - "In our search for new therapeutic agents against chronic hepatitis C, a ribonucleoside analogue, 2'-C-methylcytidine, was discovered to be a potent and selective inhibitor in cell culture of a number of RNA viruses, including the pestivirus bovine viral diarrhea virus, a surrogate model for hepatitis C virus (HCV), and three flaviviruses, namely, yellow fever virus, West Nile virus, and dengue-2 virus. "
2.	Virus Diseases (Viral Diseases) 11/23/2022 - "Treatment of GII.4-infected 3D-HIE with the polymerase inhibitor 2'-C-Methylcytidine (2CMC) and other antivirals showed a reduction in viral infection, suggesting that 3D-HIE are an excellent platform to test anti-infectives. " 12/01/2014 - "We here demonstrate that the nucleoside analogue 2'-C-methylcytidine (2'CMC) protects severe combined immunodeficient (SCID) mice against lethal FMD virus infection. "
3.	Infections 10/01/2017 - "The nucleoside analogue 2'-C-methylcytidine (2CMC), a viral polymerase inhibitor, has been shown to inhibit infection with a variety of viruses, including hepatitis C virus (HCV). " 09/10/2009 - "Phosphoramidate prodrugs of 2'-C-methylcytidine for therapy of hepatitis C virus infection."
4.	Chronic Hepatitis C 11/02/2006 - "In our search for new therapeutic agents against chronic hepatitis C, a ribonucleoside analogue, 2'-C-methylcytidine, was discovered to be a potent and selective inhibitor in cell culture of a number of RNA viruses, including the pestivirus bovine viral diarrhea virus, a surrogate model for hepatitis C virus (HCV), and three flaviviruses, namely, yellow fever virus, West Nile virus, and dengue-2 virus. "

Related Drugs and Biologics

1.	Nucleosides
2.	Prodrugs
3.	Antiviral Agents (Antivirals)
4.	phosphoramidic acid

Related Therapies and Procedures

1.	Therapeutics