gallium Ga 68 dotatate

A radioactive diagnostic agent used for POSITRON EMISSION TOMOGRAPHY (PET) imaging of SOMATOSTATIN RECEPTOR positive neuroendocrine tumors and malignant abdominal paraganglioma.

Also Known As:

68Ga-DOTATATE; 68gallium-DOTA-Tyr(3)-Thr(8)-octreotate; Ga-68 dota0-tyr3-octreotide; NETSPOT; dotatate gallium ga-68; edotreotide gallium ga-68; gallium (68ga) dota-tate; gallium 68 DOTA-octreotide; gallium 68 dotatate; gallium Ga 68-edotreotide; gallium dotatate, ga-68; gallium edotreotide ga-68; gallium ga 68-dotatoc; gallium ga-68 edotreotide; gallium-dota-octreotate, ga-68

Networked: 347 relevant articles (15 outcomes, 26 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Organometallic Compounds: 64
  - gallium Ga 68 dotatate: 347

Experts

1.	Basu, Sandip: 15 articles (02/2022 - 01/2016)
2.	Millo, Corina: 14 articles (01/2022 - 02/2016)
3.	Pacak, Karel: 11 articles (01/2022 - 02/2016)
4.	Kebebew, Electron: 11 articles (03/2019 - 02/2016)
5.	Bartenstein, Peter: 10 articles (01/2021 - 09/2010)
6.	Sadowski, Samira M: 10 articles (03/2019 - 02/2016)
7.	Herscovitch, Peter: 8 articles (01/2022 - 02/2016)
8.	Huo, Li: 7 articles (01/2022 - 09/2018)
9.	Nilubol, Naris: 7 articles (01/2022 - 02/2016)
10.	Papadakis, Georgios Z: 7 articles (05/2020 - 10/2016)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2020 - "68Ga-DOTATATE positron emission tomography (PET)/computed tomography (CT) has shown promising results in imaging of neural crest tumors (NCT). " 04/10/2016 - "These evidences have led to a growing development of new functional imaging techniques as 68Ga-DOTATATE positron emission tomography/computed tomography (PET/CT) proved useful in the management of these neoplasms. " 01/01/2021 - "A 18F-OC PET/CT study was performed in all 17 patients to localize the tumor and 68Ga-DOTATATE PET/CT was performed in 4 out of 17 patients; both studies were performed within 1 week of each other. " 11/01/2023 - "We utilize the ideal imaging type of 68Ga-DOTATATE PET/CT to produce segmentation masks from which to calculate total tumor burden metrics. " 09/01/2023 - "Of the 6 cases who had available MRI, all had metastatic cardiac lesions seen with excellent correlation with tumor localization on 68Ga-DOTATATE PET scan. "
2.	Meningioma (Meningiomas) 01/01/2023 - "68Ga-DOTATATE PET/MR imaging as an adjunct imaging technique is cost-effective in postoperative treatment planning in patients with meningiomas. " 01/01/2022 - "Here, we report on a patient with a multilocal recurrent atypical meningioma, in which 68Ga-DOTATATE PET was considerably helpful for treatment guidance and decision-making." 10/01/2017 - "Improved Detection of Transosseous Meningiomas Using 68Ga-DOTATATE PET/CT Compared with Contrast-Enhanced MRI." 10/21/2023 - "A single-institution prospective registry study was created for inclusion of patients with intracranial meningiomas who received a 68Ga-DOTATATE PET/CT to assist with radiation oncologist decision making. " 10/21/2023 - "A Prospective Registry Study of 68Ga-DOTATATE PET/CT Incorporation Into Treatment Planning of Intracranial Meningiomas."
3.	Neuroendocrine Tumors (Neuroendocrine Tumor) 01/01/2022 - "A prospective randomized, double-blind study to evaluate the diagnostic efficacy of 68Ga-NODAGA-LM3 and 68Ga-DOTA-LM3 in patients with well-differentiated neuroendocrine tumors: compared with 68Ga-DOTATATE." 01/01/2016 - "Safety and Efficacy of 68Ga-DOTATATE PET/CT for Diagnosis, Staging, and Treatment Management of Neuroendocrine Tumors." 01/01/2023 - "The current study aimed to compare 68Ga-NODAGA-Cpa-cyclo(d-Cys-amino-Phe-hydroorotic acid-d-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)-d-Tyr-NH2 (JR11) and 68Ga-DOTATATE PET/CT in patients with metastatic, well-differentiated neuroendocrine tumors. " 01/01/2023 - "Head-to-Head Comparison of 68Ga-NODAGA-JR11 and 68Ga-DOTATATE PET/CT in Patients with Metastatic, Well-Differentiated Neuroendocrine Tumors: Interim Analysis of a Prospective Bicenter Study." 08/16/2021 - "The aim of this study was to develop a PBPK model to describe organ distribution of 68Ga-DOTATATE in a population of patients without detectable neuroendocrine tumors (NETs). "
4.	Neoplasm Metastasis (Metastasis) 02/01/2021 - "The 68Ga-Dotatate PET/CT is currently considered the gold standard for assessment and follow-up of NET, including those with rare sites of metastasis such as cardiac infiltration. " 09/01/2023 - "68Ga-DOTATATE PET has excellent capability for the diagnosis of cardiac NET metastasis. " 09/01/2023 - "From a total of 1426 68Ga-DOTATATE PET/CT scans performed on patients with GEP-NET, 25 (1.75%) had cardiac uptake consistent with metastasis. " 09/01/2023 - "We sought to evaluate 68Ga-DOTATATE PET scan imaging features and associated cardiac imaging characteristics where available in those with NET cardiac metastases. " 07/13/2023 - "Neuroendocrine liver metastases treated using transarterial radioembolization: Identification of prognostic parameters at 68Ga-DOTATATE PET/CT."
5.	Insulinoma 01/01/2017 - "68Ga-DOTATATE PET/CT identifies most insulinomas and may be considered as an adjunct imaging study when all imaging studies are negative and when a minimally invasive surgical approach is planned." 03/01/2022 - "68Ga-Exendin-4 PET/CT Differentiates Insulinoma From Accessory Spleen in a Patient Presenting Indeterminate MRI and 68Ga-DOTATATE PET/CT Findings." 01/01/2020 - "A Case Report: Insulinoma in a Military Pilot Detected by 68Ga-Dotatate PET/CT." 09/01/2017 - "Results: All patients' insulinomas were shown clearly with 68Ga-DOTATATE PET/CT. " 09/01/2017 - "Methods: We performed 68Ga-DOTATATE PET/CT on 3 patients with insulinoma. "

Related Drugs and Biologics

1.	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)
2.	Somatostatin Receptors (Somatostatin Receptor)
3.	Octreotide (Sandostatin)
4.	Somatostatin (Somatotropin Release-Inhibiting Factor)
5.	Radioisotopes (Radionuclides)
6.	Peptide Receptors (Peptide Receptor)
7.	Ga(III)-DOTATOC
8.	gallium 68 PSMA-11
9.	Adrenocorticotropic Hormone (ACTH)
10.	indium-111-octreotide

Related Therapies and Procedures

1.	Radiotherapy
2.	Drug Therapy (Chemotherapy)
3.	Therapeutics
4.	Precision Medicine
5.	Thyroidectomy