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ganoderiol F

a ganoderma triterpene from Ganoderma amboinense; structure in first source

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Triterpenes: 2493
      - ganoderiol F: 3

Experts

1.	Li, Peng: 1 article (03/2022)
2.	Lin, Qiao-Fa: 1 article (03/2022)
3.	Liu, Ben-Chen: 1 article (03/2022)
4.	Shen, Cui-E: 1 article (03/2022)
5.	Wu, Min: 1 article (03/2022)
6.	Xu, Jian-Hua: 1 article (03/2022)
7.	Zhang, Zhi-Qiang: 1 article (03/2022)
8.	Zhong, Jin-Yi: 1 article (03/2022)
9.	Zhou, Yan-Fei: 1 article (03/2022)
10.	Hu, Huiping: 1 article (11/2019)

Related Diseases

1.	Neoplasms (Cancer) 11/01/2019 - "The purified compound was identified as Ganoderiol F, which induced cancer cell death. " 03/01/2022 - "In conclusion, ganoderiol F has potent effect in reversing P-glycoprotein mediated tumor multidrug resistance. " 08/15/2006 - "Ganoderiol F (GolF), a tetracyclic triterpene, was isolated from Ganoderma amboinense and found to induce senescence of cancer cell lines. "
2.	Hepatocellular Carcinoma (Hepatoma) 08/15/2006 - "Ganoderiol F, a ganoderma triterpene, induces senescence in hepatoma HepG2 cells."
3.	Squamous Cell Carcinoma (Epidermoid Carcinoma) 03/01/2022 - "Among these compounds, ganoderol B (3), ganoderone A (4), ganodermanondiol (6) and ganoderiol F (8) were shown to reverse the resistance of human oral epidermoid carcinoma cell line KBv200 to doxorubicin, and the reversal folds were 6.59, 4.70, 4.01 and 7.09, respectively. "
4.	Breast Neoplasms (Breast Cancer) 11/01/2019 - "In addition, Ganoderiol F up-regulated pro-apoptotic Foxo3, down-regulated anti-apoptotic c-Myc, Bcl-2 and Bcl-w leading to apoptosis in human breast cancer cells MDA-MB-231. " 11/01/2019 - "We found that Ganoderiol F-mediated suppression of breast cancer cell viability occurred through cell cycle arrest. " 11/01/2019 - "Hence Ganoderiol F may serve as a potential CDK4/CDK6 inhibitor for breast cancer therapy. "

Related Drugs and Biologics

1.	Member 1 Subfamily B ATP Binding Cassette Transporter
2.	Triterpenes
3.	Doxorubicin (Adriamycin)
4.	ganoderol B

Related Therapies and Procedures

1.	Therapeutics