|1.||Scozzafava, Andrea: 1 article (10/2011)|
|2.||Knaus, Edward E: 1 article (10/2011)|
|3.||Innocenti, Alessio: 1 article (10/2011)|
|4.||Supuran, Claudiu T: 1 article (10/2011)|
10/01/2011 - "A series of compounds incorporating regioisomeric phenylethynylbenzenesulfonamide moieties has been investigated for the inhibition of four human carbonic anhydrase (hCA, EC 18.104.22.168) isoforms, hCA I, II, IX and XII. Inhibition between the low nanomolar to the milliomolar range has been observed against them, with several low nanomolar and tumor-CA selective inhibitors detected. "
10/01/2011 - "Phenylethynylbenzenesulfonamide regioisomers strongly and selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic isoforms I and II."
|1.||Protein Isoforms (Isoforms)
|2.||Carbonic Anhydrases (Carbonic Anhydrase)