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NOX-B11-3

a ghrelin blocking agent

Also Known As:

spiegelmer NOX-B11-3

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleotides: 15763
  - Polynucleotides: 218
    - Oligonucleotides: 5145
      - Nucleotide Aptamers: 598
        NOX-B11-3: 1

Experts

1.	Becskei, C: 1 article (01/2008)
2.	Bilik, K U: 1 article (01/2008)
3.	Jarosch, F: 1 article (01/2008)
4.	Klussmann, S: 1 article (01/2008)
5.	Lutz, T A: 1 article (01/2008)
6.	Riediger, T: 1 article (01/2008)

Related Diseases

1.

AIDS-Related Complex (ARC)

01/01/2008 - "However, when injected at the beginning of a 14-h fasting period, the same dose of NOX-B11-3 had no effect on the c-Fos expression in the Arc of mice. "
01/01/2008 - "These results demonstrate that NOX-B11-3 is a long-acting compound, which effectively blocks the effect of exogenous ghrelin on neuronal activity in the Arc under in vitro and in vivo conditions. "
01/01/2008 - "Furthermore, NOX-B11-3 (15 mg/kg i.p.) potently suppressed ghrelin-induced (25 microg/kg s.c., 12 h after SPM injection) c-Fos expression in the Arc. "
01/01/2008 - "In electrophysiological in vitro single cell recordings, NOX-B11-3 effectively blocked the excitatory effect of ghrelin in the medial Arc (ArcM) of rats whereas the biologically inactive control SPM had no effect. "

Related Drugs and Biologics

1.	Ghrelin