azomethine

06/07/2022 - "Azomethine-thioxoimidazolidinone derivatives were studied for their inhibition potential against e5'NT enzyme along with cytotoxic potential against cancer cell lines possessing overexpression of e5'NT enzyme. "
08/15/2023 - "Anion-directed structural tuning of two azomethine-derived Zn2+ complexes with optoelectronic recognition of Cu2+ in aqueous medium with anti-cancer activities: from micromolar to femtomolar sensitivity with DFT revelation."
01/01/2022 - "Based on the Schiff base structure, the anti-cancer mechanism may be attributed to the -HC=N- azomethine group. "
01/01/2016 - "Biological Evaluation of Azomethine-dihydroquinazolinone Conjugates as Cancer and Cholinesterase Inhibitors."
01/01/2016 - "In an attempt to discover novel anti-cancer agents and potent cholinesterase inhibitors, 11 azomethine-dihydroquinazolinone conjugates were evaluated against lung carcinoma cells and cholinesterases. "

10/19/2015 - "Preference for a given regio- and stereoselectivity in the arylated product can be explained through elucidation of the mechanism for dehydration, generating azomethine ylide, and for the final re-aromatization step. "
11/01/1987 - "Analysis of electron absorption spectra and polarographic studies demonstrated that inhibition of MAO by pyrazidol resulted in dehydration of the piperazine ring in the molecule of the drug as well as in possible formation of azomethine bond at the 2-3 position, exhibiting high oxidizing activity. "
01/01/1981 - "Monoamine oxidase inhibitors /trans-2-phenylcyclopropylamine, pyrazidol, phenharmane/ belonging to the category of primary or secondary amines, in the molecule of which/ after dehydration/ formation of an azomethine bond is possible, modified the activity of membrane bound bovine brain monoamine oxidases inhibiting the deamination of serotonin and, at the same time, causing appearance of or significant increase in cadaverine--or histamine--deaminating properties. "

10/20/2023 - "By using this synthetic approach, both PUs and azomethine-capped Pus were obtained. "

11/30/2023 - "Furthermore, the biological evaluation revealed that the synthesized axially chiral azomethine imines effectively protect dorsal root ganglia (DRG) neurons by inhibiting apoptosis induced by oxaliplatin, offering a promising therapeutic approach for chemotherapy-induced peripheral neuropathy (CIPN). "

01/01/1979 - "Compounds of a special azomethine type have been tested on their activity against concanavalin A and phytohemagglutinine P mediated agglutination of leukemia L 1210 cells. "