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N-(3-oxooctanoyl)homoserine lactone

a quorum-sensing signal in Agrobacterium tumefaciens

Also Known As:

N-(3-oxo-octanoyl)homoserine lactone; OC8-HSL; OC8HSL

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Lactones: 1549
  - 4-Butyrolactone: 81
    - N-(3-oxooctanoyl)homoserine lactone: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Furans: 85
    - 4-Butyrolactone: 81
      - N-(3-oxooctanoyl)homoserine lactone: 2

Experts

1.	Faure, Denis: 2 articles (03/2010 - 05/2009)
2.	Haudecoeur, Elise: 2 articles (03/2010 - 05/2009)
3.	Cirou, Amélie: 1 article (05/2009)
4.	Dessaux, Yves: 1 article (05/2009)
5.	Raffoux, Aurélie: 1 article (05/2009)
6.	Tannières, Mélanie: 1 article (05/2009)

Related Diseases

1.	Neoplasms (Cancer) 05/01/2009 - "In the presence of agrocinopines, a constructed aiiB mutant accumulated OC8-HSL at a level 10-fold higher than that of the wild-type strain, and showed an exacerbated expression of a key QS-regulated function, conjugation of Ti plasmid (in vitro and in planta), as well as an increase of the number of emerging tumors on the host plant. " 03/01/2010 - "Over-accumulation of OC8HSL also increases severity of plant symptoms (number of emerging tumors at infection site) by an unknown mechanism. " 03/01/2010 - "The bacterial pathogen Agrobacterium tumefaciens produces the quorum-sensing (QS) signal 3-oxo-octanoylhomoserine lactone (OC8HSL) for controlling horizontal transfer of its tumor inducing (Ti) plasmid that carries both the T-DNA and the virulence genes. "
2.	Infections 03/01/2010 - "Over-accumulation of OC8HSL also increases severity of plant symptoms (number of emerging tumors at infection site) by an unknown mechanism. "

Related Drugs and Biologics

1.	Lactones
2.	T-DNA