OKT3xAntag2

a bispecific molecule constructed by conjugating monoclonal antibody OKT3 (anti-CD3) with a bombesin/GRP antagonist (Antag2); mediates growth inhibition and apoptosis of small cell lung cancer cells by activated T cells through activation and cleavage of caspase-3 and poly(ADP-ribose) polymerase in vitro and in vivo

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Bio-Agent Context: Research Results