|1.||Tao, Lijian: 9 articles (09/2015 - 05/2010)|
|2.||Hu, Gaoyun: 8 articles (09/2015 - 05/2010)|
|3.||Huang, Ling: 6 articles (09/2015 - 10/2013)|
|4.||Qin, Jiao: 6 articles (09/2015 - 05/2010)|
|5.||Peng, Zhangzhe: 6 articles (09/2015 - 05/2010)|
|6.||Hu, Gao-Yun: 5 articles (01/2015 - 09/2009)|
|7.||Zhang, Fangfang: 4 articles (09/2015 - 05/2010)|
|8.||Yuan, Qiongjing: 4 articles (09/2015 - 05/2010)|
|9.||Tao, Li-Jian: 4 articles (01/2015 - 09/2009)|
|10.||Peng, Zhang-Zhe: 4 articles (01/2015 - 09/2009)|
|1.||Diabetic Nephropathies (Diabetic Nephropathy)
10/01/2013 - "In the present study, we investigated the inhibitory effects of a novel anti-fibrotic agent, Fluorofenidone (AKF-PD), upon Nox-mediated oxidative stress and deposition of extracellular matrix (ECM) in the development of renalinterstitial fibrosis. "
09/01/2015 - "However, the mechanism by which fluorofenidone prevents renal fibrosis remains unclear. "
09/01/2015 - "Previous work has established that fluorofenidone, a pyridone agent, attenuates renal fibrosis. "
02/01/2015 - "[Effect and mechanism of fluorofenidone on organ fibrosis]."
01/01/2015 - "We evaluated the therapeutic effects of fluorofenidone (AKF-PD), a novel pyridone agent, targeting oxidative stress and fibrosis in obstructive nephropathy. "
09/01/2015 - "The aim of this study was to investigate the in vivo effects of fluorofenidone on unilateral ureteral obstruction-induced fibrosis and the involved molecular mechanism in mouse peritoneal macrophages. "
01/01/2011 - "The purpose of this study was to assess, using complete unilateral ureteral obstruction (UUO) in rats, whether fluorofenidone (AKF-PD) [1-(3-fluorophenyl)-5-methyl-2-(1H)-pyridone] inhibits renal fibrosis, and to determine whether it exerts its inhibitory function on renal fibroblast activation. "
09/01/2015 - "Fluorofenidone serves as a novel anti-inflammatory agent that attenuates ureteral obstruction-induced renal interstitial inflammation and fibrosis, possibly through the inhibition of the microtubule-associated protein kinase pathways."
11/01/2012 - "In this study, we evaluated the effects of fluorofenidone (FD), a novel pyridone agent, on a murine model of bleomycin-induced pulmonary inflammation and fibrosis. "
11/01/2012 - "Fluorofenidone attenuates bleomycin-induced pulmonary inflammation and fibrosis in mice via restoring caveolin 1 expression and inhibiting mitogen-activated protein kinase signaling pathway."
|5.||Pulmonary Fibrosis (Hamman Rich Syndrome)
02/01/2015 - "Fluorofenidone can be applied to attenuate the progression of renal, hepatic and pulmonary fibrosis."
02/01/2015 - "We previously showed that fluorofenidone (FD), a novel pyridine agent, can attenuate bleomycin-induced experimental pulmonary fibrosis and restore the production of caveolin-1. "
|4.||Protein Kinases (Protein Kinase)
|5.||Intercellular Signaling Peptides and Proteins (Growth Factors)
|7.||Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)