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5-(dimethoxymethyl)-2'-deoxyuridine

a gem diether nucleoside with anti-orthopoxvirus activity; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidine Nucleosides: 50
      - Uridine: 1186
        Deoxyuridine: 331
        5-(dimethoxymethyl)-2'-deoxyuridine: 1
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleosides: 6847
  - Pyrimidine Nucleosides: 50
    - Uridine: 1186
      - Deoxyuridine: 331
        5-(dimethoxymethyl)-2'-deoxyuridine: 1
  - Deoxyribonucleosides: 34
    - Deoxyuridine: 331
      - 5-(dimethoxymethyl)-2'-deoxyuridine: 1

Experts

1.	Fan, Xuesen: 1 article (06/2006)
2.	Keith, Kathy A: 1 article (06/2006)
3.	Kern, Earl R: 1 article (06/2006)
4.	Torrence, Paul F: 1 article (06/2006)
5.	Zhang, Xinying: 1 article (06/2006)
6.	Zhou, Longhu: 1 article (06/2006)

Related Diseases

1.

Poxviridae Infections

06/01/2006 - "To provide potential new leads for the treatment of orthopoxvirus infections, the 5-position of the pyrimidine nucleosides have been modified with a gem diether moiety to yield the following new nucleosides: 5-(dimethoxymethyl)-2'-deoxyuridine (2b), 5-(diethoxymethyl)-2'-deoxyuridine (3b), 5-formyl-2'-deoxyuridine ethylene acetal (4b), and 5-formyl-2'-deoxyuridine propylene acetal (5b). "

Related Drugs and Biologics

1.	Pyrimidine Nucleosides
2.	Nucleosides
3.	Acetals
4.	5-formyl-2'-deoxyuridine
5.	ethylene
6.	propylene (propene)