HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

PNU-142774E

dopamine receptor agonist; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - PNU-142774E: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolines: 146
      - PNU-142774E: 1

Experts

1.	Curry, James T: 1 article (03/2006)
2.	Humphrey, Stephen J: 1 article (03/2006)
3.	Turman, Chauncey N: 1 article (03/2006)
4.	Wheeler, Gracella J: 1 article (03/2006)

Related Diseases

1.	Vomiting 03/01/2006 - "Apomorphine (25 microg/kg i.v.) was intermediate to ropinirole and PNU-142774E for emesis and peak changes in MAP (-6 mm Hg), HR (+24 b/min), and QTc (+15 milliseconds) at a mean p[drug] of 3.4 ng/ml. By comparison, the class III antiarrhythmic trecetilide (2.0 mg/kg bolus) increased QTc (+58 ms) without affecting mean arterial pressure or heart rate. "

Related Drugs and Biologics

1.	Apomorphine
2.	trecetilide
3.	ropinirole (Requip)