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ZD4054

a potent endothelin receptor A antagonist that inhibits ovarian carcinoma cell proliferation
Also Known As:
trans,trans-2(4-methoxyphenyl)-4-(1-3-benzodiazol-5-yl)-1-(dibutylaminocarbonylmethyl)pyrrolidine-3-carboxylic acid; zibotentan
Networked: 39 relevant articles (12 outcomes, 18 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Morris, Thomas: 9 articles (05/2013 - 05/2009)
2. Spinella, Francesca: 7 articles (10/2012 - 06/2006)
3. Di Castro, Valeriana: 7 articles (10/2012 - 06/2006)
4. Rosanò, Laura: 7 articles (10/2012 - 06/2006)
5. Bagnato, Anna: 7 articles (10/2012 - 06/2006)
6. Natali, Pier Giorgio: 6 articles (04/2011 - 06/2006)
7. Miller, Kurt: 4 articles (05/2013 - 09/2011)
8. Cianfrocca, Roberta: 4 articles (10/2012 - 02/2009)
9. Nicotra, Maria Rita: 4 articles (04/2011 - 07/2007)
10. Liu, Glenn: 3 articles (02/2015 - 08/2008)

Related Diseases

1. Prostatic Neoplasms (Prostate Cancer)
2. Neoplasms (Cancer)
3. Colorectal Neoplasms (Colorectal Cancer)
4. Ovarian Neoplasms (Ovarian Cancer)
5. Carcinoma (Carcinomatosis)

Related Drugs and Biologics

1. ZD4054
2. Endothelin A Receptor
3. Paclitaxel (Taxol)
4. Platinum
5. Endothelins (Endothelin)
6. Pain-Free
7. Hormones
8. Carboplatin (JM8)
9. gefitinib (Iressa)
10. fulvestrant (Faslodex)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Castration
3. Drug Therapy (Chemotherapy)
4. Stents