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platensimycin

a pentacyclic ketolide (structurally similar to adamantane) connected by an amide bond to 3-amino-2,4-dihydroxybenzoic acid; inhibits cellular lipid biosynthesis; discovered while screening compounds from Streptomyces platensis bacteria in a South African soil sample with S. aureus bacteria deficient in FabF protein; structure in first source
Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Eey, Stanley T-C: 1 article (09/2014)
2. Lear, Martin J: 1 article (09/2014)
3. Schmatz, Dennis: 1 article (05/2006)
4. Young, Katherine: 1 article (05/2006)
5. Herath, Kithsiri: 1 article (05/2006)
6. Dorso, Karen: 1 article (05/2006)
7. Kodali, Srinivas: 1 article (05/2006)
8. Becker, Joseph W: 1 article (05/2006)
9. Silver, Lynn L: 1 article (05/2006)
10. Gill, Charles: 1 article (05/2006)

Related Diseases

1. Infection
2. Fatty Liver

Related Drugs and Biologics

1. Fatty Acid Synthetase Complex (Fatty Acid Synthase)