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tubulysin A

has both antiangiogenic and antineoplastic activities; structure in first source

Also Known As:

tubA compound

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - tubulysin A: 2

Experts

1.	Grigoletto, Antonella: 1 article (09/2019)
2.	Maso, Katia: 1 article (09/2019)
3.	Montagner, Isabella Monia: 1 article (09/2019)
4.	Pasut, Gianfranco: 1 article (09/2019)
5.	Rosato, Antonio: 1 article (09/2019)
6.	Schiavon, Oddone: 1 article (09/2019)
7.	Fleming, Ian N: 1 article (01/2017)
8.	Lazzari, Paolo: 1 article (01/2017)
9.	Sani, Monica: 1 article (01/2017)
10.	Spiga, Marco: 1 article (01/2017)

Related Diseases

1.	Neoplasms (Cancer) 09/01/2019 - "In addition, the ADS complex based on Trastuzumab and Protein G, conjugated with a heterobifunctional 20 kDa PEG carrying the toxin Tubulysin A, had a marked cytotoxic effect on the cancer cell line overexpressing the HER2/neu receptor, thus supporting its application in cancer therapy."
2.	Hypoxia (Hypoxemia) 01/01/2017 - "A novel hypoxia-targeting agent, KEMTUB012-NI2, was synthesized by conjugating a 2-nitroimidazole hypoxia-targeting moiety to a synthetic tubulysin, a very potent antimitotic. "

Related Drugs and Biologics

1.	Antimitotic Agents
2.	ErbB-2 Receptor
3.	Proteins (Proteins, Gene)
4.	Trastuzumab (Herceptin)
5.	azomycin

Related Therapies and Procedures

1.	Therapeutics