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lophocladine B

bioactive alkaloid from the red alga Lophocladia sp.; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Naphthyridines: 2
      - lophocladine B: 1

Experts

1.	Ballantine, David L: 1 article (04/2006)
2.	Gerwick, William H: 1 article (04/2006)
3.	Goeger, Douglas E: 1 article (04/2006)
4.	Gross, Harald: 1 article (04/2006)
5.	Hills, Patrice: 1 article (04/2006)
6.	Mooberry, Susan L: 1 article (04/2006)
7.	Murray, Thomas F: 1 article (04/2006)
8.	Valeriote, Frederick A: 1 article (04/2006)

Related Diseases

1.	Neoplasms (Cancer) 04/01/2006 - "Lophocladine A (1) displayed affinity for NMDA receptors and was found to be a delta-opioid receptor antagonist, whereas lophocladine B (2) exhibited cytotoxicity to NCI-H460 human lung tumor and MDA-MB-435 breast cancer cell lines. "
2.	Breast Neoplasms (Breast Cancer) 04/01/2006 - "Lophocladine A (1) displayed affinity for NMDA receptors and was found to be a delta-opioid receptor antagonist, whereas lophocladine B (2) exhibited cytotoxicity to NCI-H460 human lung tumor and MDA-MB-435 breast cancer cell lines. "

Related Drugs and Biologics

1.	delta Opioid Receptors (delta Opioid Receptor)
2.	N-Methyl-D-Aspartate Receptors (NMDA Receptors)
3.	lophocladine A