ADAMTS Proteins

A subfamily of ADAM proteases that are distinguished by the presence of one or more THROMBOSPONDIN type-1 repeats (TSRs). These are three-strand motifs that contain characteristic TRYPTOPHAN, ARGININE, and CYSTEINE residues respectively. In contrast to ADAM proteins, which reside on CELL MEMBRANES, ADAMTS proteases are secreted and function in the EXTRACELLULAR MATRIX.

Also Known As:

A Disintegrin And Metalloproteinase With Thrombospondin Motifs Proteins; ADAMTS Proteases; ADAMTS-Like Proteins; ADAMTSL Proteins; Adam Metallopeptidases With Thrombospondin Type 1 Motif Proteins; ADAMTS Like Protein; ADAMTS Like Proteins; Protease, ADAMTS; Protein, ADAMTS; Protein, ADAMTS-Like; Protein, ADAMTSL; A Disintegrin And Metalloproteinase With Thrombospondin Motifs Protein; ADAMTS Protease; ADAMTS Protein; ADAMTS-Like Protein; ADAMTSL Protein; Adam Metallopeptidases With Thrombospondin Type 1 Motif Protein

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Metalloproteases: 8276
        Metalloendopeptidases: 70
        ADAM Proteins: 24
        ADAMTS Proteins: 41
Carbohydrates: 22023
- Glycoconjugates: 1353
  - Glycoproteins: 24834
    - ADAM Proteins: 24
      - ADAMTS Proteins: 41
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Glycoproteins: 24834
    - ADAM Proteins: 24
      - ADAMTS Proteins: 41
  - Scleroproteins: 74
    - Extracellular Matrix Proteins: 3148
      - ADAMTS Proteins: 41

human ADAMTS18 protein

Bio-Agent Context: Research Results