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tryptophyl-histidine

Also Known As:

Trp-His

Networked: 10 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - Dipeptides: 945
      - tryptophyl-histidine: 10

Experts

1.	Matsui, Toshiro: 4 articles (07/2015 - 02/2010)
2.	Kobayashi, Yutaro: 3 articles (07/2015 - 11/2010)
3.	Tanaka, Mitsuru: 3 articles (01/2012 - 02/2010)
4.	Watanabe, Shimpei: 2 articles (11/2010 - 02/2010)
5.	Kovacs-Nolan, Jennifer: 1 article (07/2015)
6.	Mine, Yoshinori: 1 article (07/2015)
7.	Hagiya, Yoshifumi: 1 article (06/2014)
8.	Himi, Toshiyuki: 1 article (06/2014)
9.	Ishii, Isao: 1 article (06/2014)
10.	Kamata, Shotaro: 1 article (06/2014)

Related Diseases

1.	Weight Gain 09/01/1987 - "In the growth studies, weight gain was reduced 92, 79, 53, 50, 47, 31, 29, 15, 9, 4 and 0% by additions of 4% Met, Phe, Trp, His, Lys, Tyr, Thr, Ile, Arg, Val and Leu, respectively. "
2.	Leukemia 10/07/2002 - "In this study we describe abrogation of IL-7 driven proliferation and attenuated phosphotyrosine signaling by IL-7(143) (Trp-Ala) and IL-7(143) (Trp-His) in IL-7R expressing T and B leukemia cells. "
3.	Atherosclerosis 01/01/2012 - "Trp-His is the only vasoactive di-peptide known to regulate intracellular Ca(2+) ([Ca(2+)]i) and prevent the onset of atherosclerosis in mice. " 11/01/2010 - "Our previous findings regarding the biological activities of small peptides revealed that a di-peptide, Trp-His (WH), could play a role in the prevention of vascular lesions, including cell proliferation and atherosclerosis. " 02/01/2010 - "Vasodilating dipeptide Trp-His can prevent atherosclerosis in apo E-deficient mice."
4.	Infections 09/01/2000 - "With lymphogranuloma venereum biovar strain 434, little difference in the influx of representative amino acids Trp, His, and Lys or the analogue 2-aminoisobutyric acid (AIB) was observed during infection. " 12/10/2009 - "In search of short antimicrobial peptides, which represent a possible alternative for lead structures to fight antibiotic resistant microbial infections, a series of synthetic peptide analogues based on Trp-His and His-Arg structural frameworks have been prepared and found to be active against several Gram-negative and Gram-positive bacterial strains as well as against a fungal strain with MIC values of the most potent structures in the range of 5-20 microg/mL ((IC(50) in the range of 1-5 microg/mL). "
5.	Body Weight (Weight, Body) 02/01/2010 - "Administration of Trp-His did not affect growth parameters such as body weight and feeding efficiency (P>0.1). " 07/08/2015 - "Trp-His (100 or 250 mg/kg body weight/day) was administered for 14 days to BALB/c mice, and 5% dextran sodium sulfate (DSS) was administered to induce colitis in the last 7 days. "

Related Drugs and Biologics

1.	Phosphotyrosine
2.	Interleukin-7 (Interleukin 7)
3.	arginylvaline
4.	methionylphenylalanine
5.	Peptides (Polypeptides)
6.	Dipeptides
7.	Cytokines
8.	Dextrans (Dextran)
9.	Apolipoproteins E (ApoE)
10.	Anti-Bacterial Agents (Antibiotics)