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LY226936

Appetite Depressants; caused reduced food intake when administered to obese Zucker rats

Also Known As:

methylcarbamothoic acid-S-(4,5-dihydro-2-thiazolyl) ester

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Sulfur Compounds: 278
  - Thiazoles: 392
    - LY226936: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Thiazoles: 392
      - LY226936: 1

Related Diseases

1.

Body Weight (Weight, Body)

09/01/1994 - "LY226936 administered orally and centrally to obese Zucker rats suppresses food intake and body weight gain."
09/01/1994 - "LY226936 reduced the food consumption after a single oral dose of 50 and 100 mg/kg. On chronic oral administration to meal-fed obese (5 to 35 mg/kg. once daily) and to fed obese and lean (15 mg/kg. twice daily) Zucker rats, LY226936 reduced food intake and body weight gain for periods ranging from 40 to 48 days. "

Related Therapies and Procedures

1.	Oral Administration