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PCM3-II
a growth inhibitor; Isolated from mycelium of Poria cocos
Networked:
1
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Carbohydrates: 22023
Polysaccharides: 15383
Glucans: 1624
beta-Glucans: 499
PCM3-II: 1
Experts
1.
Cheung, Peter C K
: 1 article (03/2006)
2.
Chiu, Lawrence C-M
: 1 article (03/2006)
3.
Ooi, Vincent E C
: 1 article (03/2006)
4.
Zhang, Mei
: 1 article (03/2006)
Related Diseases
1.
Neoplasms (Cancer)
03/01/2006 - "
The MTT study showed that PCM3-II reduced proliferation and viability of the MCF-7 cells dose-dependently, so that the cancer-cell growth was decreased by 50% of the control level at 400 microg/ml of the glucan.
"
2.
Breast Neoplasms (Breast Cancer)
03/01/2006 - "
In this study, the growth-inhibitory effect of PCM3-II was further explored on the human breast carcinoma MCF-7 cells in vitro.
"
03/01/2006 - "
The time effect of PCM3-II was then investigated by treating the breast cancer cells with 400 microg/ml of the glucan for 24, 48 and 72 h, respectively.
"
03/01/2006 - "
The dose effect of PCM3-II was studied by incubating the breast cancer cells with 12.5-400 microg/ml of the glucan for 72 h.
"
Related Drugs and Biologics
1.
Glucans